Jupiter Scleral Lenses in the Management of Chronic Graft Versus Host Disease

Abstract

Jupiter scleral lenses can relieve symptoms of KCS and may improve vision in patients with cGVHD.

Use of mini scleral contact lenses in moderate to severe dry eye

“…Scleral contact lenses have shown to be safe and effective in managing dry eye symptoms [32][33][34][35][36][37] by providing a fluid cushion for the cornea to rest in and protecting cornea from the rubbing effects of the keratinized lids. This may result in regression of the disease, at least partly, by breaking the vicious circle of inflammation.…”

Scleral lens for ocular surface disease

“…Three of these are large cohort studies that include analyses on OSD patient subgroups (Severinsky and Millodot, 2010;Stason et al, 2010;Gumus et al, 2011), while three more reports examined the effect of scleral RGP lenses in populations with one specific surface disease (Schornack et al, 2008;Tougeron-Brousseau et al, 2009;Rathi et al, 2011). Also included in the twelve publications are four case reports or series of single disease entities reporting outcome measures demonstrating the effectiveness of scleral RGP lenses (Schornack and Baratz, 2009;Grover et al, 2010;Gumus et al, 2010;Schornack, 2011), and two case series describing innovative uses of scleral lenses in patients with other ocular complications secondary to OSD (Lim et al, 2009;Tanhehco and Jacobs, 2010).…”

“…Two reports from 2007 (Jacobs and Rosenthal, 2007;Takahide et al, 2007) report on the role of scleral RGP lenses in chronic GvHD. The Jupiter lenses that are fit by these investigators (Schornack et al, 2008) are commercially available to eye care professionals, and "may therefore be more accessible to patients who could potentially benefit from this intervention. "…”

“…Scleral rigid gas-permeable lenses for ocular chronic graft-versus-host disease Schornack et al (2008) report on 5 patients, 10 eyes, that present with keratoconjunctivitis sicca secondary to GvHD that was not responsive to standard ocular intervention. Their patients were fitted with Jupiter scleral lenses (Medlens Innovations, Front Royal, VA or Essilor Contact Lens, Inc., Dallas, TX).…”

Bandage and scleral contact lenses for ocular graft‐versus‐host disease after allogeneic haematopoietic stem cell transplantation

“…Keratoconjunctivitis sicca (KCS) is the most common manifestation of ocular GvHD and can lead to severe cases of punctate and filamentary keratitis, causing invalidating discomfort, irreversible ocular surface damage and visual loss (Takahide et al 2007;Schornack et al 2008).…”