Junction Nevus—nevocarcinoma

The Malignant Tumours of the Skin

“…The diagnosis is confirmed by the microscope. There appears to be no risk of initiating or increasing malignancy in a suspected lesion by the performance of a biopsy provided a report is obtained within two to four days and excision performed then if necessary (Traub, 1947 ;Sachs, et al, 1947 ;-Becker, 1949 ;Winer, Weidman, Mont gomery-personal communication, 1949 ;McGovern, 1952 ;Lewis, 1953 ;Erank, 1954, and others with whom I agree). In general it is wise to remove small lesions as a whole for biopsy purposes.…”

“…Meirowski and Freeman (1951) suggest that filtrable melanin granules may represent the carrier or causative agent. It is considered by many that intra-epidermal and intra-dermal nsevi do not become malignant (Traub, 1947 ;Sachs, et al, 1947 ;McGovern, 1952 ;Lewis, 1953, ten Seldam and others). When malignant changes occur it is in the junctional or compound type naevus where clear cell melanoblasts and mature naevus cells are distributed in the basal layer of the epidermis and the adjacent layers of the epidermis and dermis.…”

Diagnosis and Treatment of Malignant Melanoma in Bulgaria

“…However there are many (Hess, 1948;Miescher, 1955), including the author, who believe that simple excision of a melanotic tumour is dangerous. Disastrous metastases have sometimes followed this procedure (Becker, 1954;Sachs et al, 1947). Our own experience of biopsy is as follows.…”