“…Particular interest has been focused on the relationship between hypertension and/or coronary heart disease and occupational stressors, operationalized as specific job problems, high job demands, job dissatisfaction, and low job rewards.13-'1 This work has yielded inconsistent findings, with some studies showing positive associations13"14"16-25 and others indicating null or negative associations.612152- 29 Work by Karasek and his colleagues suggests that there is a strong association between job strain, conceptualized as the joint effect of high job demands and low decision latitude or control, and an increased prevalence and/or incidence of coronary heart disease and myocardial infarction when traditional risk factors such as age, race, cholesterol, and smoking are controlled for.14,18 20 Also, job strain has recently been shown to be positively associated with elevated diastolic blood pressure and a higher left-ventricularmass index in a case-control study of employees from several occupations (odds ratio of 3.1). 25 Although some studies have used case-control or prospective designs, 18,25 most of the studies using Karasek does not permit evaluations of the associations between workers' self-perceptions of their jobs and disease status.…”