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doi:10.14294/water.2019.7

Cited by 2 publications

(29 citation statements)

References 78 publications

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“…A nanoparticle-exclusion zone shell can radiate and thus the model based on it can explain the observations like as follows, 9,30 1. Vigorously shaken ultra-high dilution of lithium chloride and sodium chloride were irradiated by X-and y-rays at 77 K and then let them warm up to room temperature.…”

Section: Discussionmentioning

confidence: 99%

“…30 "The Nanoparticle-EZ Shell Model" is successful in explaining homeopathic medicine and its bizarre appearing properties. 9,30 For example, it is a common observation that homeopathic medicines lose their properties around 70 degrees C and above. This neutralization can be explained because heat favors EZ growth and excessive heat does so excessively reverting the information containing modified EZ to the generic one.…”

Section: How Ultra-high Dilutions May Work As Nanomedicinesmentioning

confidence: 99%

“…Equipped with the ability to observe the principle of similars, homeopathic phenomenon could be evolved through hormesis as being exclusively therapeutic and deeper in action than hormesis to support life on the toxic Earth. 9 This is a possible reason why the pre-and post-conditioning hormesis research methodology can help to study homeopathic phenomenon which Hahnemann exploited to establish homeopathy.…”

Section: Difference Between Hormesis and Homeopathy: The Principle Of Similarsmentioning

confidence: 99%

“…8 Toxic substances that do not exhibit hormesis can do so after their potentization, at least those with which life evolved. 9 Medicinal effects of serially diluted succussed solutions are not confined to substances conventionally used in homeopathy as sourcedrugs. Chemicals like histamine, 10 thyroxine, 11 and aspirin 12 diluted homeopathically, even far beyond Avogadro's limit, have found biological models showing opposite effects to those from their pharmacological doses.…”

Section: Introductionmentioning

confidence: 99%

“…Chemicals like histamine, 10 thyroxine, 11 and aspirin 12 diluted homeopathically, even far beyond Avogadro's limit, have found biological models showing opposite effects to those from their pharmacological doses. 9 Similarly diluted sodium butyrate, a promising therapeutic agent for cancer treatment which targets epigenetic pathways, found modulating the transcriptome of HEK 293 cells. 13 Also, the taxane anti-cancer drugs paclitaxel and docetaxel, used in chemotherapy, diluted similarly showed differential effects on the genes of breast cancer cells without being cytotoxic.…”

Section: Introductionmentioning

confidence: 99%

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Exploring Possible Mechanisms of Hormesis and Homeopathy in the Light of Nanopharmacology and Ultra-High Dilutions

Ullman¹

2021

Dose-Response

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Serially diluted succussed solutions of a suitable drug/toxic substance can exhibit physicochemical and biological properties even far beyond Avogadro’s limit defying conventional wisdom. They can show hormesis, and homeopathy uses them as medicines. Many studies confirm that they can have an impact on gene expression different than controls. Water in the exclusion zone phase can have memory but for a short period. However, the nanoparticle as the physical substrate can hold information. Nanoparticle and exclusion zone duo as nanoparticle-exclusion zone shell can provide a prolonged memory. The Nanoparticle-Exclusion Zone Shell Model may be an important step toward explaining the nature and bioactivity of serially diluted succussed solutions used as homeopathic medicines. This model may also provide insight into the workings of hormesis. Hormesis is the primary phenomenon through which homeopathic phenomenon may have evolved exhibiting the principle of similars. Hahnemann exploited it to establish homeopathy. The nanoparticle-exclusion zone shells present in the remedy, selected on the principle of similars, can be patient-specific nanoparticles in a symptom syndrome-specific manner. They can carry the drug-specific information for safer clinical applications in an amplified form for high yielding. It suggests homeopathy is a type of nanopharmacology.

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Section: Discussionmentioning

confidence: 99%

Section: How Ultra-high Dilutions May Work As Nanomedicinesmentioning

confidence: 99%

Section: Difference Between Hormesis and Homeopathy: The Principle Of Similarsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Exploring Possible Mechanisms of Hormesis and Homeopathy in the Light of Nanopharmacology and Ultra-High Dilutions

Ullman¹

2021

Dose-Response

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2022

WATER

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Evolutionary biologists are confused and divided, some even condemning their theories as just history or storytelling. They are confined to elaborative evolution while self-organization pervades biology. A quantum approach including self-organization and emergence as the physics of complex systems is essentially required, with water, a two-phase liquid, one phase of which is quantum coherent. These physical realities are instrumental for the evolution, even of the properties of an environmental stressor, through its turbulent serial dilution. Such dilution happens spontaneously in nature, and defying conventional wisdom, can cause even epigenetic and genomic effects. Electromagnetic potential and the phase can store information as biological agents. Homeopathy, incredibly, uses such dilutions as medicines. In this statistical, nondeterministic, and quantum mechanically elusive world, the real-life empirical observations of homeopathy are evidence of their biological effects. The proposed theory suggests that the environmental stressor is a more crucial driver of evolution than the organism or its genes, evolutionary products in themselves. Its four-dimensional geometrical template could evolve in the organism during its evolutionary history what it can now disturb in health or restore during sickness. Thus, directing selforganization through morphogenesis, such stressors turn-by-turn led the whole organism's evolution to adapt better. They gradually built up a critical state in the organism, followed by its rapid specification. Their random permutations led to biodiversity. Thus, this theory may cover evolution from its deep molecular interior, while contemporary theory covers its macroscopic exterior; these theories complement each other. This view finds an immediate test application in regenerative medicine and may lead to quantum medicine.

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Cited by 2 publications

References 78 publications

Exploring Possible Mechanisms of Hormesis and Homeopathy in the Light of Nanopharmacology and Ultra-High Dilutions

Exploring Possible Mechanisms of Hormesis and Homeopathy in the Light of Nanopharmacology and Ultra-High Dilutions

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