Jejunectomy Can Reduce Excessively Elevated Portal Pressure After Major Hepatectomy in Beagle Dogs

Pancreatic injury after major hepatectomy: a study in a porcine model

“…The reason may be that the total intrahepatic portal vasculature is decreased after major hepatectomy and intrahepatic portal vascular resistance increases as a result [33]. Portal hypertension after major hepatectomy has been reported previously as well [34][35][36]. A mild increase was observed after 12 h (P \ 0.05) of reperfusion, and this level persisted until the end of the current experiment.…”

Influence of Preoperative Chemotherapy on CT Volumetric Liver Regeneration Following Right Hemihepatectomy

“…However, an important advantage was that the patients enrolled in this study were included in a multicenter prospective RCT on a different subject, for which chemotherapy was not part of the selection criteria and therefore no selection bias took place. It was assumed that percentage early liver volume increase assessed with CT volumetry reflects liver regeneration and also liver function; however, part of the liver volume increase may be caused by edema or hepatic swelling due to high portal pressure [29]. The future liver remnant volume and postoperative true liver remnant ( V RLV7days ) were measured differently; for future studies it would probably be better to conduct a direct measure of the left liver lobe pre‐ and postoperatively.…”

Desferrioxamine Attenuates Pancreatic Injury after Major Hepatectomy under Vascular Control of the Liver: Experimental Study in Pigs

“…It involves portal hypertension during the Pringle maneuver leading to direct congestion of the pancreas [7], postoperative portal hypertension due to the decreased intrahepatic portal vasculature following massive resections [37–40], spillage of cytokines, oxidative substances, and reactive oxygen species which produce tissue injury [3, 20]. …”