2016
DOI: 10.1016/j.oraloncology.2016.03.005
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Jaw osteoradionecrosis and dental extraction after head and neck radiotherapy: A nationwide population-based retrospective study in Taiwan

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Cited by 55 publications
(53 citation statements)
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“…Patients with post-RT dental extractions are at an increased risk of developing ORN [20, 3133]. However, in this study 82% of the patients who developed ORN had no prior traumatic event or dentoalveolar procedure prior to development of ORN.…”
Section: Discussionmentioning
confidence: 65%
See 1 more Smart Citation
“…Patients with post-RT dental extractions are at an increased risk of developing ORN [20, 3133]. However, in this study 82% of the patients who developed ORN had no prior traumatic event or dentoalveolar procedure prior to development of ORN.…”
Section: Discussionmentioning
confidence: 65%
“…The local risk factors include tumor site, tumor stage, proximity of the tumor to bone, radiation field, dose of radiation, poor oral hygiene, and associated trauma, such as dental extraction/surgery before or after RT. Systemic factors include co-morbidities, smoking and drinking alcohol, immunodeficient status, and infection [1520]. The aims of this study are: (1) to report the current prevalence of ORN in patients with oral cavity cancer (OCC) and oropharyngeal cancer (OPC) treated with IMRT between 2004 and 2013 in our institution; and (2) to evaluate the correlation between various risk factors [radiation dose, periodontal status, alcohol and smoking] and the development of ORN.…”
Section: Introductionmentioning
confidence: 99%
“…A recent retrospective cohort study of 1759 patients with head and neck cancer in Taiwan concluded that a tooth extraction time less than half a year after head and neck radiotherapy or during the head and neck radiotherapy period, and extraction tooth number ≤ 5 would significant lower the ORN prevalence. 28 Multidisciplinary approach is mandatory in the management of the patient. Further improvement in therapeutic and treatment options is required in order to reduce ORN complications and its negative impact on the quality of life.…”
Section: Case Reportmentioning
confidence: 99%
“…Post-RT dental extraction is well-recognized as patient-related risk factor for ORNJ [28][29][30]. A systematic review reported that the incidence rate of ORNJ after tooth extraction in irradiated patients was 7% [31].…”
Section: Discussionmentioning
confidence: 99%