Jamaicolides A-D, four sesquiterpene lactones from Calea jamaicensis

Ober, Alfonso G.; Fischer, Nikolaus H.; Parodi, Felix J.

doi:10.1016/0031-9422(86)80020-6

Cited by 9 publications

(6 citation statements)

References 14 publications

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“…The EA from C. jamaicensis (Asteraceae) was the only EA that moderately inhibited the growth of F. equiseti , suggesting that it produces a highly polar antifungal metabolite(s). This species was documented to have leishmanicidal activity and to be useful for treating colds and stomach pain [ 57 , 58 ], but the present report is the first on its antifungal activity. Among 125 Calea species, only C. urticifolia has been tested against fungal pathogens, but it had no activity against F. oxysporum [ 25 , 59 ].…”

Section: Discussionmentioning

confidence: 91%

Extracts from Six Native Plants of the Yucatán Peninsula Hinder Mycelial Growth of Fusarium equiseti and F. oxysporum, Pathogens of Capsicum chinense

et al. 2020

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Fusarium equiseti strain FCHE and Fusarium oxysporum strain FCHJ were isolated from the roots of wilting habanero pepper (Capsicum chinense Jacq.) seedlings with root rot. Toward developing a biorational control of these serious phytopathogenic strains, ethanolic (EE) and aqueous (AE) extracts of different vegetative parts of 40 tropical native plants of the Yucatán Peninsula were screened for antifungal activity. Extracts of six out of 40 assayed plants were effective, and the most inhibitory extracts were studied further. EEs from Mosannona depressa (bark from stems and roots), Parathesis cubana (roots), and Piper neesianum (leaves) inhibited mycelial growth of both strains. Each active EE was then partitioned between hexane and acetonitrile. The acetonitrile fraction from M. depressa stem bark (MDT-b) had the lowest minimum inhibitory concentration of 1000 µg/mL against both pathogens and moderate inhibitory concentration (IC50) of 462 against F. equiseti and 472 µg/mL against F. oxysporum. After 96 h treatment with EE from M. depressa stem bark, both strains had distorted hyphae and conidia and collapsed conidia in scanning electron micrographs. Liquid chromatography–ultraviolet–high resolution mass spectrometry analysis revealed that the major component of the fraction was α-asarone. Its antifungal effect was verified using a commercial standard, which had an IC50 of 236 µg/mL against F. equiseti and >500 µg/mL against F. oxysporum. Furthermore, the P. cubana hexane fraction and P. neesianum acetonitrile fraction had antifungal activity against both Fusarium pathogens. These compounds provide new options for biorational products to control phytopathogenic fungi.

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Section: Discussionmentioning

confidence: 91%

Extracts from Six Native Plants of the Yucatán Peninsula Hinder Mycelial Growth of Fusarium equiseti and F. oxysporum, Pathogens of Capsicum chinense

et al. 2020

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“…All these biflavones bear the same 3' ,8"-linked nuclei with one to three methoxyl substituents. During our work on the HPLC separation of biflavones from Ginkgo biloba leaves (8,9), we detected traces of a bi-flavone which represents 2 % of the total biflavones content. On the basis of mass, 1H-NMR, and other spectral and chromatographic data, it was identified as amentoflavone (1).…”

Section: H3c Ohmentioning

confidence: 97%

“…Green autumnal leaves of Ginkgo biloba L. trees were collected at the Botanical Garden of Strasbourg, according to the seasonal variations of the biflavone content which shows a higher yield in October (9).…”

Section: H3c Ohmentioning

confidence: 99%

New Sesquiterpenoids fromChrysanthemum indicumvar.tuneful

Mladenova¹,

Tsankova²,

Hung³

1988

Planta Med

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“…Flavonoid profile of Calea plants consisted of four chalcones (192–195), one isoflavone (196), one flavonone (197), five O ‐heteroside flavonoids (198–202), and seven flavones (203–209). Genkwanin (204), 7‐ O ‐methylacacetin (205), and acacetin (206) are the major aglycone flavones in Calea (Chaurasiya et al, ; Do Nascimento, et al, ; Do Nascimento, Salvador, Candido, Ito, et al, ; Herz & Kumar, ; Kohler et al, ; Martinez, Naveda‐Diaz, & Joseph‐Nathan, ; Martinez, Sanchez, & Joseph‐Nathan, ; Ober et al, ; Ober & Fischer, ; Ober, Fischer, & Parodi, ; Ober, Urbatsch, & Fischer, ; Ortega, Lopez, & Maldonado, ).…”

Section: Chemical Constituentsmentioning

confidence: 99%

“…(Lourenço, Akisue, & Roque, 1981). Genkwanin (204), 7-O-methylacacetin (205), and acacetin (206) are the major aglycone flavones in Calea (Chaurasiya et al, 2016;Kohler et al, 2002;Martinez, Naveda-Diaz, & Joseph-Nathan, 1988;Martinez, Sanchez, & Joseph-Nathan, 1987;Ober et al, 1985b;Ober, Fischer, & Parodi, 1986;Ober, Urbatsch, & Fischer, 1985a;Ortega, Lopez, & Maldonado, 1989).…”

Section: Chromones and Chromanonesmentioning

confidence: 99%

The genus Calea L.: A review on traditional uses, phytochemistry, and biological activities

Lima

Souza

Silva

et al. 2018

Phytotherapy Research

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Calea L. is a genus of shrubs and perennial herbs belonging to Asteraceae family. It is a very well‐known genus, consisting of approximately 125 neotropical species. Calea genus is a rich source of phytochemicals, and some of its species have been used in folk medicine to treat several health problems such as diabetes, arterial hypertension, respiratory and gastrointestinal disorders, gastric ulcers, and inflammation. Many studies have demonstrated the pharmacological potential of this genus, including antinociceptive, antihypertensive, antidiarrheal, antimicrobial, anti‐inflammatory, antidiabetic, antiproliferative, and cytotoxic activities. Moreover, bioactive constituents related to these properties are mainly sesquiterpene lactones and phenolic derivatives. In this review, we compiled the literature data up to December 2016, furnishing a comprehensive survey about medicinal uses, chemistry, and biological activities from Calea species. Bibliographic search was performed in several search engines using “Calea” as search keyword. Further, a manual literature search of references found in the selected studies was also conducted. There was no initial time limit.

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Jamaicolides A-D, four sesquiterpene lactones from Calea jamaicensis

Cited by 9 publications

References 14 publications

Extracts from Six Native Plants of the Yucatán Peninsula Hinder Mycelial Growth of Fusarium equiseti and F. oxysporum, Pathogens of Capsicum chinense

Extracts from Six Native Plants of the Yucatán Peninsula Hinder Mycelial Growth of Fusarium equiseti and F. oxysporum, Pathogens of Capsicum chinense

New Sesquiterpenoids fromChrysanthemum indicumvar.tuneful

The genus Calea L.: A review on traditional uses, phytochemistry, and biological activities

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