Israel guidelines for the management of neonatal hyperbilirubinemia and prevention of kernicterus

Kaplan, Michael; Merlob, Paul; Regev, Rivka

doi:10.1038/jp.2008.20

Cited by 76 publications

(50 citation statements)

References 47 publications

(56 reference statements)

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“…[2][3][4][5][6][7] The AAP guideline 1 has been widely adopted in the United States and elsewhere but there is no similar guideline in the United States for the treatment of infants <35 weeks gestation. In lieu of such direction, neonatal intensive care units (NICUs) have established their own criteria for the use of phototherapy and exchange transfusion in these infants, most often based on birth weight or gestational age.…”

Section: Introductionmentioning

confidence: 99%

An approach to the management of hyperbilirubinemia in the preterm infant less than 35 weeks of gestation

et al. 2012

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We provide an approach to the use of phototherapy and exchange transfusion in the management of hyperbilirubinemia in preterm infants of <35 weeks of gestation. Because there are limited data for evidence-based recommendations, these recommendations are, of necessity, consensusbased. The recommended treatment levels are based on operational thresholds for bilirubin levels and represent those levels beyond which it is assumed that treatment will likely do more good than harm. Long-term follow-up of a large population will be needed to evaluate whether or not these recommendations should be modified.

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Section: Introductionmentioning

confidence: 99%

An approach to the management of hyperbilirubinemia in the preterm infant less than 35 weeks of gestation

et al. 2012

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“…It depends on how high the general level of bilirubin of the studied neonates was, how bilirubin was measured, and what kind of a standard for phototherapy was used. Although AAP guideline is considered to be a global standard, the evidence base for any standards of phototherapy is weak and various standards are used as national guidelines even among the developed countries ( Table 2) [2][3][4][5][6]. In Japan no guideline has been established, and several standards are used ( Table 1) [7][8][9].…”

Section: Discussionmentioning

confidence: 99%

“…Various standards are used even among the developed countries [1]. Many of standards are categorized by gestational age including the guideline of American Academy of Pediatrics (AAP), because prematurity is one of a risk factors for kernicterus [2][3][4][5][6], and some standards are categorized by birth weight-for example the standards in Japan are all categorized by birth weight [7][8][9]. In the standards like Canadian guideline; low birth weight (<2500 g) is independently listed as a risk factor [5].…”

Section: Introductionmentioning

confidence: 99%

Percentile analysis of plasma total bilirubin—How different will the rate of phototherapy for jaundice of neonates be by different standards?

Nagao¹,

Watanabe²,

Yokota³

2012

OJPed

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Phototherapy of a jaundiced neonate is usually started when bilirubin exceeds a threshold in the standard. There are several standards used in the developed countries even though the guideline of American Academy of Pediatrics is considered to be a global standard. Although the purpose of phototherapy is the prevention of kernicterus, nowadays the prevalence of kernicterus in otherwise healthy term neonates in the developed countries is rare. Meanwhile several potential adverse effects of phototherapy have been reported. In the present study we tried to estimate how different the rate of phototherapy for the jaundice of neonates at lower risk of kernicterus would be by different standards. For this purpose, we utilized the records of plasma total bilirubin (TB) values of 1893 healthy neonates of 38 weeks and more which were measured on day 6 for the percentile analysis. However, this database did not include the TB values of the neonates who received phototherapy by day 6. Then the database was corrected with an assumption that TB on day 6 would have been normally distributed if no phototherapy had been performed. The mean and the standard deviation (SD) of corrected database were 11.29 mg/dl (193 μmol/l) and 3.63 mg/dl (62 μmol/l), respectively. Using a standard distribution with these mean and SD, the percents of TB values which exceed 18.0, 19.0, 20.0 and 21.0 mg/dl on day 6 were estimated 3.22%, 1.70%, 0.82% and 0.35%, respectively. Results of the present report would help to estimate the relative rate of phototherapy that is performed for the neonates who are term and otherwise healthy by different standards.

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“…The risk of developing hyperbilirubinemia is higher if the baby has acidosis, hypoxia or hypoglycemia, all of which prevent indirect bilirubin levels from bonding with albumin (Çavuşoğlu, 2011). Establishing standardized approaches and monitoring in the treatment of this physiological or pathological process has become a need recognized all over the world and countries such as the United States, Canada and Israel have prepared guidelines for this (American Academy of Pediatrics, 2004;Kaplan & Merlob, 2008;Sgro & Campbell, 2006).…”

Section: Cause and Types Of Jaundicementioning

confidence: 99%

Breastfeeding After a Cesarean Delivery

Kuğuoğlu¹,

Yıldız²,

Tanir³

et al. 2012

Cesarean Delivery

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Israel guidelines for the management of neonatal hyperbilirubinemia and prevention of kernicterus

Cited by 76 publications

References 47 publications

An approach to the management of hyperbilirubinemia in the preterm infant less than 35 weeks of gestation

An approach to the management of hyperbilirubinemia in the preterm infant less than 35 weeks of gestation

Percentile analysis of plasma total bilirubin—How different will the rate of phototherapy for jaundice of neonates be by different standards?

Breastfeeding After a Cesarean Delivery

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