Isoprenylated resorcinol derivatives from Glycyrrhiza acanthocarpa

First Total Syntheses of Amorfrutin C and pseudo‐Amorfrutin A

“…[1] Amorfrutin A was first extracted from Glycyrrhiza acanthocarpa by Ghisalberti et al [2] Biological studies revealed that amorfrutin A has potent antimicrobial, [3] anticancer, [4] antiinflammatory, [5] and antidiabetes [6] activities. [1] Amorfrutin A was first extracted from Glycyrrhiza acanthocarpa by Ghisalberti et al [2] Biological studies revealed that amorfrutin A has potent antimicrobial, [3] anticancer, [4] antiinflammatory, [5] and antidiabetes [6] activities.…”

“…The amorfrutins are a family of compounds that contain a characteristic planar 2-hydroxybenzoic acid core with prenyl, benzyl, or alkyl residues, and a methoxy or hydroxy group attached at the C-4 position; they usually show diverse biological activities. [1] Amorfrutin A was first extracted from Glycyrrhiza acanthocarpa by Ghisalberti et al [2] Biological studies revealed that amorfrutin A has potent antimicrobial, [3] anticancer, [4] antiinflammatory, [5] and antidiabetes [6] activities. Mitscher et al extracted amorfrutin A and amorfrutin B from Amorpha fruticosa.…”

Phenolic Constituents of Licorice (Glycyrrhiza Species)

“…RL-V (142) G. glabra root (259) Licoriphenone (175) G. uralensis root (282) Kanzonol Q (189) G. uralensis root (261) (Coumarin) Glyasperin E (197) G. aspera root (289) Inflacoumarin A (232t G. infiata root (211,306,307) (Neoflavone) Gancaonin K (245) G. pallidiflora root (312) No name (296) G. acanthocarpa aerial part (358) No name (297) Uralenneoside ( The trivial name "licuraside" is used in Chemical Abstracts and "liquiraside" is used in Doklady (Eng!. trans!.…”

“…have reported the isolation of two dihydrostilbenes (294 and 295) having a prenyl group and two prenylphenols (296 and 297) from the leaves and terminal branches of G. acanthacarpa (Lind!) J.B. Black collected in Western Australia (358).…”

Two New Stilbenoids from Cajanus cajan

“…], which belongs to the Cajanus genus, one of the most valuable perennial or annual leguminous food crops in Asia, Africa and some parts of tropical and subtropical areas of the world, has been reported to contain stilbenoids, flavonoids, coumarin, and other kinds of constituents [2 -7], yet the number of reported compounds is quite small. Our interest in the bioactivities of stilbenoids and the attempt to enrich the chemical constituents in pigeon pea led to the isolation of two new stilbenoids, cajanotone (1) and cajanamide A (2), six known ones (3)(4)(5)(6)(7)(8) and four known dihydroflavones (9)(10)(11)(12) (Fig. 1).…”