1987
DOI: 10.1055/s-2006-962720
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Isopimpinellin is not Phototoxic to Viruses and Cells

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Cited by 14 publications
(7 citation statements)
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“…The possible mechanism of action could be related to previous reports in which certain furanocoumarins can not only intercalate into deoxyribonucleic acid (DNA) and create cross-links with thymidine residues, but also can form covalent links to apoproteins and permanently inactivate cytochrome P450 enzymes [ 34 ]. It has been reported in the literature that compound 5 possesses antimicrobial [ 35 ], spasmogenic [ 36 ], cardiovascular [ 37 ], cancer chemopreventive [ 38 ], vasorelaxing [ 39 ], and non-phototoxic effects [ 40 , 41 ]. Additionally, compound 1 possesses antimutagenic effects [ 42 ] and it is a cancer chemopreventive agent [ 43 ].…”
Section: Resultsmentioning
confidence: 99%
“…The possible mechanism of action could be related to previous reports in which certain furanocoumarins can not only intercalate into deoxyribonucleic acid (DNA) and create cross-links with thymidine residues, but also can form covalent links to apoproteins and permanently inactivate cytochrome P450 enzymes [ 34 ]. It has been reported in the literature that compound 5 possesses antimicrobial [ 35 ], spasmogenic [ 36 ], cardiovascular [ 37 ], cancer chemopreventive [ 38 ], vasorelaxing [ 39 ], and non-phototoxic effects [ 40 , 41 ]. Additionally, compound 1 possesses antimutagenic effects [ 42 ] and it is a cancer chemopreventive agent [ 43 ].…”
Section: Resultsmentioning
confidence: 99%
“…man, 1978). Isopimpinellin is not a photosensitizer (Ashwood-Smith et al, 1983;Hudson et al, 1987). Limettin is 200 times less photoactive than bergapten on rabbit skin (Naganuma et al, 1985) although it was not phototoxic at 1% on stripped human skin (Marzulli and Maibach, 1970).…”
Section: Introductionmentioning
confidence: 99%
“…28) (Beier et al, 1983b). Isopimpinellin is not a photosensitizer (Ashwood- Smith et al, 1983;Hudson et al, 1987) and, therefore, has not been quantified in many studies. Scheel et al (1963) described another linear furanocoumarin, 4,5',8-trimethylpsoralen (TMP) as being the causal agent for photosensitized skin reactions in farm workers.…”
Section: Celerymentioning
confidence: 99%