Isopimaranes and eremophilanes from the wood-decay fungus Xylaria allantoidea BCC 23163

Isaka, Masahiko; Yangchum, Arunrat; Supothina, Sumalee; Chanthaket, Rungtiwa; Srikitikulchai, Prasert

doi:10.1016/j.phytol.2014.01.011

Cited by 20 publications

(10 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, the core structure of abietanes is closely related to the pimaranes, which are commonly encountered in fungi. Pimaranes were even already isolated from various Xylaria species (Isaka et al, 2012(Isaka et al, , 2014, indicating that the biosynthetic pathway for tricyclic terpenoids might be common within the family.…”

Section: Resultsmentioning

confidence: 99%

Botryane, noreudesmane and abietane terpenoids from the ascomycete Hypoxylon rickii

et al. 2015

View full text Add to dashboard Cite

In the course of our screening for new bioactive natural products, a culture of Hypoxylon rickii, a xylariaceous ascomycete collected from the Caribbean island Martinique, was identified as extraordinary prolific producer of secondary metabolites. Ten metabolites of terpenoid origin were isolated from submerged cultures of this species by preparative HPLC. Their structures were elucidated using spectral techniques including 2D NMR and HRESIMS. Three of the compounds were elucidated as new botryanes (1-3) along with three known ones, i.e. (3aS)-3a,5,5,8-tetramethyl-3,3a,4,5-tetrahydro-1H-cyclopenta[de]isochromen-1-one (4), (3aS,8R)-3a,5,5,8-tetramethyl-3,3a,4,5,7,8-hexahydro-1H-cyclopenta[de]isochromen-1-one (5) and botryenanol (6). Further three new sesquiterpenoids featured a 14-noreudesmane-type skeleton and were named hypoxylan A-C (7-9); the diterpenoid rickitin A (10) contains an abietane-type backbone. Compounds 1, 2, 3, 7, and 10 showed cytotoxic effects against murine cells.

show abstract

Section: Resultsmentioning

confidence: 99%

Botryane, noreudesmane and abietane terpenoids from the ascomycete Hypoxylon rickii

et al. 2015

View full text Add to dashboard Cite

show abstract

“…The isolation of all compounds reported here for the first time from endophytes of O. sanctum. Coriloxin was previously isolated from the xylariaceous endophytic fungus obtained from plants and Xylariaceae allantoidea [18,19]. Coriloxin exhibited antimicrobial and plant growth inhibitory activities [18].…”

Section: Resultsmentioning

confidence: 99%

Oxygenated Secondary Metabolites from Endophytic Fungi Isolated From Ocimum sanctum

Shoeb

Khandaker

Nahar

2015

J. Basic Appl. Sci.

View full text Add to dashboard Cite

Ocimum sanctum Linn (Tulsi), an important medicinal plant of Bangladesh is used for antimicrobial, antiinflammatory and antiulcer activities. Eleven endophytic fungi were isolated from O. sanctum. The fungal strain, labeled as OS-005, was cultivated at large scale on the potato dextrose agar semi solid medium and was extracted with ethyl acetate. Repeated column chromatography of the parent extract by normal phase silica gel and one of its fraction by Sephadex LH-20 afforded linoleic acid, R (-)-glycerol monolinoleate, 9,10,11-trihydroxy-(12Z)-12-octadecenoic acid, ergosterol, ergosterol peroxide, 1,8-O-dimethylaverantin, coriloxin, and a new natural product named sanctumol. The structures of these compounds were elucidated unequivocally by UV, IR, MS and a series of 1D & 2D NMR analyses.

show abstract

“…From the wood-decay fungus X. allantoidea. , xylallantins A–C ( 116–118 ), along with compounds 24 , 25 and 115 , were isolated [ 47 ]. From the fungicolous fungus X. longipes, Xylarilongipins A ( 119 ) and B ( 120 ) ( Figure 11 ) both with an unusual bicyclo [2.2.2] octane structure, and compound 26 , were obtained.…”

Section: Isopimaranementioning

confidence: 99%

Pimarane Diterpenes from Fungi

Yao

2022

Pharmaceuticals

View full text Add to dashboard Cite

Pimarane diterpenes are a kind of tricyclic diterpene, generally isolated from plant and fungi. In nature, fungi distribute widely and there are nearly two to three million species. They provide many secondary metabolites, including pimarane diterpenes, with novel skeletons and bioactivities. These natural products from fungi have the potential to be developed into clinical medicines. Herein, the structures and bioactivities of 197 pimarane diterpenes are summarized and the biosynthesis and pharmacological researches of pimarane diterpenes are introduced. This review may be useful improving the understanding of pimarane diterpenes from fungi.

show abstract

Isopimaranes and eremophilanes from the wood-decay fungus Xylaria allantoidea BCC 23163

Cited by 20 publications

References 23 publications

Botryane, noreudesmane and abietane terpenoids from the ascomycete Hypoxylon rickii

Botryane, noreudesmane and abietane terpenoids from the ascomycete Hypoxylon rickii

Oxygenated Secondary Metabolites from Endophytic Fungi Isolated From Ocimum sanctum

Pimarane Diterpenes from Fungi

Contact Info

Product

Resources

About