Isolation, structural characterization and bioactivities of polysaccharides and its derivatives from Auricularia-A review

Isolation, purification, characterization, and immunomodulatory effects of polysaccharide from Auricularia auricula on RAW264.7 macrophages

“…Although there are many published studies on the health benefits of all species of Auricularia in both humans and animals, and an increase in the study of kinds of polysaccharide's immune function (Miao et al., 2020). However, little research investigates the A. auricula polysaccharide's systematically over the whole cycle from isolation, purification, and its immunomodulatory properties, which is one of the main species of Auricularia , particularly cultivated in Heilongjiang and Jilin province, northeast region of China (Miao et al., 2020).…”

“…Although there are many published studies on the health benefits of all species of Auricularia in both humans and animals, and an increase in the study of kinds of polysaccharide's immune function (Miao et al, 2020). However, little research investigates the A. auricula polysaccharide's systematically over the whole cycle from isolation, purification, and its immunomodulatory properties, which is one of the main species of Auricularia, particularly cultivated in Heilongjiang and Jilin province, northeast region of China (Miao et al, 2020).This study used A. auricula as a raw material and determined the best extraction conditions for A. auricula polysaccharide (AAP) by a one-factor-at-a-time test and response surface methodology experiment. Then, following further separation and purification of crude AAP using DEAE cellulose and Sephadex G-100, it was characterized though high-performance gel permeation chromatography (HPGPC), HPLC, and FT-IR.…”

Recent progress in the research of Angelica sinensis (Oliv.) Diels polysaccharides: extraction, purification, structure and bioactivities

“…Therefore, breaking up cell wall of A. sinensis could release polysaccharides easily and improve the extraction yield. Some different technologies could improve the extraction efficiencies, including microwaveassisted treatments and ultrasonic processing [32]. Zhao et al identified the optimum operational conditions for maximizing polysaccharides yield through response surface methodology as ultrasound power 180 W, ultrasound time 45 min using a water: material ratio (w:w) of 7:1 at 90 °C.…”

Effects of Selenium Auricularia cornea Culture Supplementation on Growth Performance, Antioxidant Status, Tissue Selenium Concentration and Meat Quality in Growing-Finishing Pigs

“…It has been generally considered that Auricularia polysaccharides (AP) are the major bioactive substance. Various bioactivities of AP have been reported, including immunomodulatory, antioxidant, antitumor activities, hepatoprotective [5]. Wu et al (2010) [6] found that AP could modulate the immune functions of aged mice by increasing the weights of the thymus and spleen.…”

“…Wu et al (2010) [6] found that AP could modulate the immune functions of aged mice by increasing the weights of the thymus and spleen. In the opinion of Miao et al (2020) [5], AP could activate the innate immune system and effector cells, including T-lymphocytes, B-lymphocytes, macrophages, and natural killer cells to express cytokines, such as IL-1β, TNF-α, IL-6, and IL-10. Five water-soluble APs from different varieties were all observed to have scavenging activities against superoxide, 2,2-diphenyl-1-picrylhydrazyl (DPPH), and hydroxyl radicals [7].…”