“…Stress on the visual system and ocular surface in this context is considered to be the cumulative discomfort caused by prolonged near work, particularly with computer use and reduced blink rate, often in a reduced humidity environment. 31,32,[34][35][36][37] Because the blink is the primary physical mechanism for expressing meibomian oil into the tear film, 4,38,39 a reduced blink rate during near work will result in reduced lipid layer thickness and/or MG output. [40][41][42][43] However, as it is not yet known whether the secretory characteristics of an individual MG, in the absence of significant stress, vary throughout the day, the impact of significant stress on individual MG function cannot be fully understood.…”