Isolation of Mucorspp from patients with otitis media and its sensitivity to antifungals

Abstract

The current study dealt with patients with otitis media, where the fungus was isolated from different pathological conditions, and the patients were distributed according to age, sex, residence, and chronic diseases.The fungal species isolated from these patients were diagnosed, and the focus was on Mucor as it is dangerous and may cause black fungus disease, as it was diagnosed phenotypically and molecularly by polymerase chain reaction (PCR) and a drug sensitivity test was conducted. The results showed that men are more susceptible to infection than women, and adults are more susceptible than adolescents and children, and chronic diseases increased the incidence.The study showed an average ability of Mucor spp to produce hydrolytic enzymes, which makes it dangerous only for patients with low immunity. The study also showed that the fungus is resistant to antifungals except for fluconazole, amphotericin B, and ketoconazole, where the diameter of inhibition was 32, 14, and 10 mm, respectively.