Isolation of drug residues from tissues by solid phase dispersion

Barker, Steven A.; Long, Austin R; Ce, Short

doi:10.1016/s0021-9673(01)89689-8

Cited by 455 publications

(192 citation statements)

References 7 publications

Supporting

Mentioning

184

Contrasting

Unclassified

Order By: Relevance

“…A spare and rapid extraction technique is matrix solid phase dispersion (MSPD) [8,9]. As carotenoids are very sensitive to both light and air, an optimized combination of analytical sample preparation, separation, and detection techniques has to be used.…”

Section: Sample Preparationmentioning

confidence: 99%

Characterization of bixin by LC‐MS and LC‐NMR

Rehbein

Dietrich

Grynbaum

et al. 2007

J of Separation Science

View full text Add to dashboard Cite

An overview upon modern analytical techniques for the isolation, separation, and structural identification of the essential bioactive carotenoid bixin is given. Isolation from biological matrices is performed by matrix solid phase dispersion (MSPD). The extract is separated with shape‐selective C30 columns. Structural assignment of the separated compounds is done by online LC‐MS and capillary HPLC‐NMR.

show abstract

Section: Sample Preparationmentioning

confidence: 99%

Characterization of bixin by LC‐MS and LC‐NMR

Rehbein

Dietrich

Grynbaum

et al. 2007

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…MSPD based on dispersion of sample onto an adsorbent (generally Florisil or C18) is a technique that allows extraction and clean up in one step. 11,12 This technique has recently been applied, using acid alumina, to extract several OCPs in biotical samples. 13 However MSPD procedure need longer analytical time generally and its limit of determination (LOD) is limited.…”

Section: Introductionmentioning

confidence: 99%

Matrix Solid Phase Dispersion‐Accelerated Solvent Extraction for Determination of OCP Residues in Fish Muscles

Shen

Yuan

Zhang

et al. 2011

J Chinese Chemical Soc

View full text Add to dashboard Cite

A rapid, sensitive and accurate matrix solid phase dispersion-accelerated solvent extraction (MSPD-ASE) method for selective determination of sixteen organochlorine pesticide (OCP) residues in fish samples has been developed and validated. 2 g fresh fish muscle was dispersed with 10 g anhydrous sodium sulfate and 2 g acid alumina thoroughly, and loaded into the stainless-steel extraction cell containing 6 g of acid alumina and 10 g anhydrous sodium sulfate. The temperature 60°C and two extraction cycles of 5 min gave adequate extraction efficiency using DCM-hexane (3:7, v/v) mixture as solvent. Not only the lipids, but also other co-extracts, which peaks mostly located in the forepart of chromatograms and maybe interfere the identification or quantitation of analytes, were eliminated exhaustively, while analytes were extracted selectively. Sixteen OCPs were identified by retention time of standards and quantified using mirex as internal standards. These detected OCPs were confirmed by GC-MS in real samples. The performance of proposed method was evaluated and validated: the detection limits were 0.008-0.05 ng g -1 , relative standard deviations were 1.9-5.0%, and recoveries were 91.0-104.1% spiked at 10 ng g -1 level. The accuracy and precision of proposed method were equal to or better than that of traditional Soxhlet extraction method.

show abstract

“…Barker [74] defined MSPD procedures as those that use dispersing sorbents with chemical modification of the silica surface (e.g. C18, C8, etc.).…”

Section: Manual Sample Extraction Techniquesmentioning

confidence: 99%

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

Kinsella

O’Mahony

Malone

et al. 2009

Journal of Chromatography A

181

View full text Add to dashboard Cite

A comprehensive review is presented on the current trends in sample preparation for isolation of veterinary drugs and growth promotors from foods. The objective of the review is to firstly give an overview of the sample preparation techniques that are applied in field. The review will focus on new techniques and technologies, which improve efficiency and coverage of residues. The underlying theme to the paper is the developments that have been made in multi-residue methods and particularly multi-class methods for residues of licensed animal health products, which have been developed in the last couple of years. The role of multi-class methods is discussed and how they can be accommodated in future residue surveillance.

show abstract

Isolation of drug residues from tissues by solid phase dispersion

Cited by 455 publications

References 7 publications

Characterization of bixin by LC‐MS and LC‐NMR

Characterization of bixin by LC‐MS and LC‐NMR

Matrix Solid Phase Dispersion‐Accelerated Solvent Extraction for Determination of OCP Residues in Fish Muscles

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

Contact Info

Product

Resources

About