Isolation of antioxidative and ACE inhibitory peptides from protein hydrolysate of skipjack (Katsuwana pelamis) roe

Angiotensin Converting Enzyme Inhibition with Antiradicalar Activity of Thornback Ray Gelatin Hydrolysate: Determination and Separation of Peptide Fractions

“…With increasing acetonitrile concentration, higher hydrophobic residues were eluted; the highest ACE inhibitory activity of SF9 and SF10 might be due to its high hydrophobicity Jung, et al [34]. Similar result was reported by Intarasirisawat, et al [35] when studying the ACE inhibitory activity of RP-HPLC peptide fractions of defatted skipjack roe hydrolysed by Alcalase.…”

Antioxidant and angiotensin I converting enzyme (ACE) inhibitory activities of date seed protein hydrolysates prepared using Alcalase, Flavourzyme and Thermolysin

“…Several researchers have identified the bioactive peptides from various protein hydrolysates using LC-MS/MS (Ghassem, Arihara, Babji, Said, & Ibrahim, 2011;Intarasirisawat, Benjakul, Wu, & Visessanguan, 2013;Théolier, Hammami, Labelle, Fliss, & Jean, 2013). The molecular weights of peptides from date seed protein hydrolysates dissolved in 0.1% TFA and 50 mM ammonium acetate in 2% CHCl3/methanol solvent system are presented in Table 3.…”

Characterization and comparative assessment of antioxidant and ACE inhibitory activities of thornback ray gelatin hydrolysates

“…In addition, ACE inactivates the bradykinin which is a vasodilator. Potent ACE inhibitory hydrolysates and peptides have been isolated from different food sources such as sea cucumber gelatin (Zhao et al, 2007), rice (Chen et al, 2013) and skipjack roe (Intarasirisawat, Benjakul, Wu, & Visessanguan, 2013). Such bioactive peptides are inactive in their original protein, and can be released to active form through the intestinal digestion or hydrolysis by proteases (Wu et al, 2008).…”