Isolation of a new cycloartanoid triterpene from leaves of Lansium domesticum novel skin-tumor promotion inhibitors

Nishizawa, Masatoyo; Emura, Makoto; Yamada, Hidetoshi; Shiro, Motoo; Chairul,; Hayashi, Yûji; Tokuda, Harukuni

doi:10.1016/s0040-4039(01)93813-4

Cited by 38 publications

(28 citation statements)

References 10 publications

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“…Hal yang sama diperoleh pada profil KLT dari ekstrak etanol kulit langsat (KLE) dan ekstrak etil asetat kulit langsat (KLEA) masing-masing adanya spot yang menunjukkan golongan senyawa flavonoid dan steroid/terpenoid. Hal ini sesuai dengan beberapa literatur yang menjelaskan bahwa L.domesticum memiliki kandungan senyawa flavonoid dan steroid/terpenoid (Klungsupya et al, 2015;Nishizawa et al, 1982Nishizawa et al, , 1989Tanaka et al, 2002).…”

Section: Hasil Dan Pembahasanunclassified

SCREENING OF ANTIOXIDANTS, ANTI-AGING AND TYROSINASE INHIBITORY ACTIVITIES OF ETHANOLIC AND ETHYL ACETATE EXTRACTS OF FRUIT FLESH AND FRUIT PEEL LANGSAT (Lansium domesticum Corr) IN VITRO

2017

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Section: Hasil Dan Pembahasanunclassified

SCREENING OF ANTIOXIDANTS, ANTI-AGING AND TYROSINASE INHIBITORY ACTIVITIES OF ETHANOLIC AND ETHYL ACETATE EXTRACTS OF FRUIT FLESH AND FRUIT PEEL LANGSAT (Lansium domesticum Corr) IN VITRO

2017

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“…Some researchers have reported the findings on antimalarial tetranortriterpenoids from langsat seeds (Nishizawa et al 1988;Saewan et al 2006) and isolation of cycloartanoid triterpene from langsat leaves (Nishizawa et al 1989). Judging from the physical form of the fruit and seeds, most common dryers are suitable to be employed to dry langsat and its seeds.…”

Section: Langsatmentioning

confidence: 99%

Drying of Exotic Tropical Fruits: A Comprehensive Review

Fernandes

Law

Mujumdar

2010

Food Bioprocess Technol

165

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This paper provides a capsule overview of recent experimental studies dealing with the drying of a large assortment of tropical and subtropical fruits, also called "exotic" fruits. The term exotic includes a number of tropical fruits that are not yet commonly found in global markets but do have the potential to do so in view of their appearance, taste, and textural and nutritional quality parameters. As the consumer is seeking diverse tastes and flavors without compromising on quality, it is logical to expect the market for dried exotic fruits to increase over the next decade. This review covers diverse drying techniques, drying kinetics, and key quality parameters of dried fruits.

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“…Bark of this plant can be used for the treatment of dysentery, malaria and as an antidote of scorpion poisoning [13]. Lansic acid, lansiolic acid, dukunolide and cycloartanoid triterpene have been previously isolated from this plant and some of them showed an inhibitory effect on skin tumor promotion [6,[14][15][16]. The aqueous leaf extracts of this plant were also found to reduce Plasmodium falciparum growth in culture [23].…”

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confidence: 99%

Effects of Central Kalimantan Plant Extracts on Intraerythrocytic Babesia gibsoni in Culture

subeki

Matsuura

Yamasaki

et al. 2004

The Journal of Veterinary Medical Science

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ABSTRACT. The inhibitory effects of 45 plant extracts selected from Central Kalimantan, Indonesia on Babesia gibsoni in vitro and their acute toxicity to mice were evaluated. Of these plant extracts studied, Arcangelisia flava, Curcuma zedoaria, Garcinia benthamiana, Lansium domesticum and Peronema canescens were found to have appreciable antibabesial activity with IC 50 values from 5.3 to 49.3 µg/ml without acute toxicity in mice at the intraperitoneal dose of 0.7 g/kg of body weight.KEY WORDS: antibabesial activity, Babesia gibsoni, Central Kalimantan plant, toxicity.J. Vet. Med. Sci. 66(7): 871-874, 2004 Canine babesiosis is a tick-borne disease of wild and domestic dogs caused by intraerythrocytic parasites, Babesia gibsoni and Babesia canis. The parasites are widely distributed in tropical and subtropical areas worldwide and cause hemolytic anemia of the affected dogs [2,5,22]. Diminazene aceturate (Ganazeg) is an aromatic diamidine used extensively for the treatment of B. gibsoni infection in affected areas of the world [5]. Although the medicine can reduce the severity of clinical signs and the mortality associated with the disease, it sometimes induces severe side effects such as weakness, irritability, paralysis, non-responsiveness to stimuli and fatal central nervous system haemorrhage [3]. Dogs that have recovered from the babesiosis also commonly become chronic carriers, thereby posing a source of infection for other dogs and ticks. Notably, production of this drug was recently stopped. Therefore, for the treatment of B. gibsoni infected dogs, an alternative chemotherapeutic agent having few side effects is urgently needed. One possible source of such affordable treatment lies in the use of plant extracts.Central Kalimantan, Indonesia is well known for its green tropical vegetation and peat swamp forests. Its diverse nature and uses are claimed to have medicinal properties. No data are available to assess the extent to which these plant extracts can be used for the treatment of B. gibsoni infected dogs. The aims of the present study were to evaluate the inhibitory effects of the Central Kalimantan plant extracts on the B. gibsoni in vitro and their acute toxicity to mice.Forty-five plants were collected from Central Kalimantan, Indonesia based on ethnopharmacological characteristics. These plants were identified at the Herbarium Bogoriense, Indonesia. Voucher specimens were deposited at the Department of Research and Development for Biology, Indonesian Institute of Sciences, Bogor. Each plant sample (10 g) was boiled for 30 min in 200 ml of water twice. The boiling water was freeze-dried and then ground into powder.To evaluate the antibabesial activity, the powder of plant extracts was dissolved in dimethyl sulfoxide (DMSO) and further diluted with RPMI 1640 medium supplemented with sodium pyruvate (0.1 mg/ml), glutamine (0.3 mg/ml), sodium bicarbonate (2 mg/ml), penicillin (100 units/ml) and streptomycin (100 µg/ml). The final DMSO concentration was not more than 0.1%. B. gibsoni used in this stu...

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Isolation of a new cycloartanoid triterpene from leaves of Lansium domesticum novel skin-tumor promotion inhibitors

Cited by 38 publications

References 10 publications

SCREENING OF ANTIOXIDANTS, ANTI-AGING AND TYROSINASE INHIBITORY ACTIVITIES OF ETHANOLIC AND ETHYL ACETATE EXTRACTS OF FRUIT FLESH AND FRUIT PEEL LANGSAT (Lansium domesticum Corr) IN VITRO

SCREENING OF ANTIOXIDANTS, ANTI-AGING AND TYROSINASE INHIBITORY ACTIVITIES OF ETHANOLIC AND ETHYL ACETATE EXTRACTS OF FRUIT FLESH AND FRUIT PEEL LANGSAT (Lansium domesticum Corr) IN VITRO

Drying of Exotic Tropical Fruits: A Comprehensive Review

Effects of Central Kalimantan Plant Extracts on Intraerythrocytic Babesia gibsoni in Culture

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