“…The round yeast shape was also kept in a mutant strain where most α-glucan was replaced by 1,3-mannan, as well as in the parent strain that presented only reduced amounts of α-glucan due to the effect of multiple sub-culturing (San Blas et al, 1976, 1977b). Later analysis of cell wall polysaccharides proved that their composition, however, could vary not only with culture conditions, but also among isolates (San Blas and Vernet, 1977; San Blas and San Blas, 1982; San Blas et al, 1984), and especially in mutants with defects in phase transition (San Blas et al, 1977a; Hallak et al, 1982; San Blas and San Blas, 1992). At that time, these mutants were useful to review the models of dimorphism (Kanetsuna et al, 1972; Kanetsuna, 1981; San Blas and San Blas, 1984, 1994).…”