Isolation and properties of bovine parvovirus type 1 from Japanese calves

Inaba, Yuji; Kurogi, H.; Takahashi, Eiji; Sato, Kunihiko; Tanaka, Yoshio; Goto, Yuhei; Omori, T.; Matumoto, Minoru

doi:10.1007/bf01250507

Cited by 16 publications

(5 citation statements)

References 10 publications

(10 reference statements)

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“…The high viral concentrations found in these organs might reflect their elevated content of blood and blood cells. Besides, during the histological investigation the presence of basophilic inclusions in the renal tissue could be observed and these might represent parvoviral accumulations, similar to other reports for parvoviruses both in vivo (Hayes et al, 1979 ; Bestetti and Zwahlen, 1985 ; Porter et al, 1988 ; Decaro and Buonavoglia, 2012 ) and in vitro (Inaba et al, 1973 ; Oleksiewicz et al, 1996 ). Surprisingly, all blood or serum samples collected during various years were positive at a rather constant load: we could detect viremia 8 years prior to the death of the animal.…”

Section: Discussionsupporting

confidence: 86%

Persistent viremia by a novel parvovirus in a slow loris (Nycticebus coucang) with diffuse histiocytic sarcoma

et al. 2014

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Cancer is one of the leading health concerns for human and animal health. Since the tumorigenesis process is not completely understood and it is known that some viruses can induce carcinogenesis, it is highly important to identify novel oncoviruses and extensively study underlying oncogenic mechanisms. Here, we investigated a case of diffuse histiocytic sarcoma in a 22 year old slow loris (Nycticebus coucang), using a broad spectrum virus discovery technique. A novel parvovirus was discovered and the phylogenetic analysis performed on its fully sequenced genome demonstrated that it represents the first member of a novel genus. The possible causative correlation between this virus and the malignancy was further investigated and 20 serum and 61 organ samples from 25 animals (N. coucang and N. pygmaeus) were screened for the novel virus but only samples collected from the originally infected animal were positive. The virus was present in all tested organs (intestine, liver, spleen, kidneys, and lungs) and in all banked serum samples collected up to 8 years before death. All attempts to identify a latent viral form (integrated or episomal) were unsuccessful and the increase of variation in the viral sequences during the years was consistent with absence of latency. Since it is well known that parvoviruses are dependent on cell division to successfully replicate, we hypothesized that the virus could have benefitted from the constantly dividing cancer cells and may not have been the cause of the histiocytic sarcoma. It is also possible to conjecture that the virus had a role in delaying the tumor progression and this report might bring new exciting opportunities in recognizing viruses to be used in cancer virotherapy.

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Section: Discussionsupporting

confidence: 86%

Persistent viremia by a novel parvovirus in a slow loris (Nycticebus coucang) with diffuse histiocytic sarcoma

et al. 2014

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“…Since then this mode of transmission was reported for RV (Ferm and Kilham, 1964;Kilham and Ferm, 1964), LuIII (Soike et al, 1976), MVM , FPV (Kilham and Margolis, 1966;Kilham et al, 1967;Csiza et al, 1971), PPV (for reference see Mengeling et al, 1980;Mengeling, 1981), BPV (Storz et al, 1972;Inaba et al, 1973b;Storz et al, 1978b), as well as for ADV (Padgett et al, 1967;Porter et al, 1977a;Porter and Cho, 1980). Factors such as the time of gestation at which the animals acquire infection, their state of immunity, and last but not least, the genetic composition of the infecting virus apparently determine the outcome of in utero infection.…”

Section: B Transmissionmentioning

confidence: 87%

“…As far as the serologic relationship between the viruses grouped in Table III is concerned, cross neutralization brought about no new points of view. No antigen in common to the various viruses could be revealed by such tests (Moore, 1962b;Portell a, 1963;Lum and Schreiner, 1963;Toolan, 1964;Crawford, 1966;Gorham et al, 1966;Johnson, 1967b;Johnson et ai., 1967;Scott et ai., 1970b;Cross and Parker, 1972;Storz et ai., 1972;Inaba et al, 1973b;Joo et al, 1975;Siegl, 1976;Tratschin et al, 1982). Slight antigenic differences between individual isolates of one and the same virus, however, apparently are more readily detected than by means of HI.…”

Section: Serum Neutralizationmentioning

confidence: 99%

Biology and Pathogenicity of Autonomous Parvoviruses

Siegl

1984

The Parvoviruses

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“…An inconsistent hemagglutination also occurs using erythrocytes from dog, horse, sheep, goat, hamster, duck, goose, and rat [6,33] . The hemagglutination reaction is mediated by binding of BPV to glycophorin A, which is an important N -acetylneuraminic acid-containing (sialyl) glycoprotein, on erythrocytes [34] .…”

Section: Clinical Manifestation and Pathogenesismentioning

confidence: 99%

Animal Bocaviruses: A Brief Review

Manteufel

Truyen²

2008

Intervirology

116

117

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The recently discovered human Bocavirus has been preliminary classified into the genus Bocavirus of the family Parvoviridae. Animal bocaviruses have been known in veterinary medicine since the early 1960s. This paper reviews the current knowledge about the two eponymous members of the genus: bovine parvovirus (BPV) and canine minute virus (CnMV). In contrast to other parvoviruses, bocaviruses contain a third open reading frame in the mid of the genome encoding for a highly phosphorylated non-structural protein, NP1, whose function has not yet been determined. The VP1-unique region of BPV and CnMV contains a phospholipase A₂ sequence motif. Both viruses cause diseases of the gastrointestinal and respiratory tract and are known to infect fetuses and to cause reproductive disorders. Especially young animals suffer from disease, whereas in adults subclinical infection is common. Clinical signs include diarrhea, vomiting, dyspnea, embryonic/fetal death after transplacental infection early and abortion late in gestation. Both viruses have in common that they are widespread in their host species as worldwide serosurveys indicate. For BPV it has been shown that sialated glycoproteins mediate hemagglutination reaction and function as receptor for virus attachment on permissive cells.

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Isolation and properties of bovine parvovirus type 1 from Japanese calves

Cited by 16 publications

References 10 publications

Persistent viremia by a novel parvovirus in a slow loris (Nycticebus coucang) with diffuse histiocytic sarcoma

Persistent viremia by a novel parvovirus in a slow loris (Nycticebus coucang) with diffuse histiocytic sarcoma

Biology and Pathogenicity of Autonomous Parvoviruses

Animal Bocaviruses: A Brief Review

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