Animal Bocaviruses: A Brief Review

Manteufel, J.; Truyen, Uwe

doi:10.1159/000173734

Cited by 116 publications

(129 citation statements)

References 78 publications

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“…However, examining whether HBoV was the cause of vomiting in individuals whose samples we analyzed in the current study was not within the scope of this project. It is important to note that we isolated the virus in respiratory-associated specimens even though the virus has also been associated with diarrhea in humans [23], which is also a feature common in animal parvovirus infections [24]. These unique characteristics reflect the many aspects of virus infection that are yet to be explored, especially in the developing world where gastroenteritis and diarrhea cases are high.…”

Section: Discussionmentioning

confidence: 94%

Molecular detection and phylogenetic analysis of Kenyan human bocavirus isolates

Misigo

Mwaengo

Mburu

2014

J Infect Dev Ctries

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Introduction: The commonly expected causative agents associated with flu-like symptoms in Kenya are the classical viral pathogens identifiable as influenza virus, adenovirus, parainfluenza virus, enteroviruses, respiratory syncytial virus (RSV) and rhinovirus. However, newer agents have been identified globally that present with illnesses clinically indistinguishable from those caused by the classical pathogens; one of them is human bocavirus. Methodology: A total of 384 specimens were analyzed, primarily to determine if the emerging human bocavirus (HBoV) infections exist in Kenya as coinfections with other respiratory viruses and to describe the genotype of the virus in circulation. In brief, viral nucleic acids were extracted from culture supernatants, amplified by PCR, and sequenced. Results: HBoV DNA was amplified from 1.8% of screened specimens. Coinfection with parainfluenza virus, adenovirus, and enterovirus was 2.5%, 2%, and 1.4%, respectively. Multiple coinfections consisting of HBoV plus two other viruses were found in 3% of specimens. Isolation occurred in the months of January, March, April, August, and November. Retrospective review of clinical parameters indicated that all the individuals complained of non-specific symptoms, mainly fever, coughs, nasal stuffiness, runny noses, and vomiting. Phylogenetically, the GenBank deposited sequences of this study's isolates cluster closely to the reference strain NC_07455 (HBoV1). Conclusion: Coinfections with human bocavirus (HBoV1) occur in Kenya, and high incidence might primarily be during the early stages of children's lives.

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Section: Discussionmentioning

confidence: 94%

Molecular detection and phylogenetic analysis of Kenyan human bocavirus isolates

Misigo

Mwaengo

Mburu

2014

J Infect Dev Ctries

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“…In the first half of the pregnancy, stillbirth and embryo resorption process can occur after infection. In the second half, observed a larger number of stillborn and weak puppies [71].…”

Section: Canine Minute Virusmentioning

confidence: 93%

“…The clinical signs found in CnMV infection may vary, be unapparent, or apparent as respiratory problems, enteric disease and reproductive disorders [71]. Infected puppies less than 1 month of age may have mild symptoms or accelerated death, depression, lack of appetite, acute myocarditis, respiratory failure and enteritis.…”

Section: Canine Minute Virusmentioning

confidence: 99%

“…In relation to the histopathologic findings, viral presence in the epithelial cells of the intestinal crypts and cardiomyocytes are observed. Other changes found are hyperplasia of the interstitial crypts, myocardial necrosis, pneumonia, and depletion of lymphocytes in the thymus and other lymphoid tissues [71]. The samples for diagnosis may vary mostly from foetal or neonatal tissues of the myocardium, intestine, lungs, kidneys and faeces.…”

Section: Canine Minute Virusmentioning

confidence: 99%

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Infectious Causes of Abortion, Stillbirth and Neonatal Death in Bitches

Antunes¹,

CarvalhoFreire²,

Oliveira³

et al. 2016

Canine Medicine - Recent Topics and Advanced Research

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Problems in gestational development in dogs can be determined by infectious and noninfectious causes. Among the non-infectious causes, trauma during pregnancy, genetic characteristics of the animal, deficit nutrition, thyroid dysfunction, maternal problems and hormonal disorders are found. The majority of the cases are in relation to infectious diseases, one should consider viral, bacterial, fungal and protozoal, which can interfere directly or indirectly in the foetal development. The progression of foetal development may be affected by the direct action of the microorganisms to overcome the placenta, but they are also able to affect pregnancy and release placental toxins by inflammatory processes and, may still cause maternal pathologies, which entail problems such as hyperthermia, hypoxia and endotoxemia, which can result in abortion. Several diseases can trigger pregnancy loss in dogs. This action can be direct by microorganisms, as well as indirectly triggering other problems that lead to abortion. This chapter discusses the infectious aetiologies of reproductive failures (abortion, stillbirth and neonatal death) in bitches.

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“…It is a small (22 nm), non-enveloped virus with icosahedral structure. BPV is a pathogen of cattle found worldwide that causes severe gastroenteritis in calves, mild respiratory infection, and may cause reproductive failure (Manteufel & Truyen, 2008;Sandals et al, 1995). It is a contamination risk for commercially prepared bovine serum and bovine-derived products.…”

Section: Introductionmentioning

confidence: 99%