Isolation and Identification of Pathogenic Bacteria Causing Otitis Media in Misan Governorate

Hateet, Rashid Rahim; Banoon, Shaima Rabeea; Mohammed, Muhanad Mahdi

doi:10.22207/jpam.16.2.66

Cited by 3 publications

(2 citation statements)

References 47 publications

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“…[21][22][23][24][25] However, other studies have reported that S. aureus was the most prevalent pathogen. 3,26,27 Recently, Udden et al 28 revealed that Proteus spp. are common pathogens that caused ear infections.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Antibiotic Sensitivity Profile of Bacteria in Patients with Ear Infections

Al-Tulaibawi¹,

Aal-Aaboda²,

Al-Qaesy³

2023

J. Pure Appl. Microbiol.

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Ear infections are extremely common and widespread otological disorders in children and adults. Accordingly, it is critical to identify the etiological factors and determine their antimicrobial susceptibility to achieve successful clinical outcomes. Ear swab samples were collected from patients aged 10-69 years at the Al-Sadar Teaching Hospital in Al-Amara city and cultured using the standard microbiological methods. The VITEK 2-compact system was used to analyze the bacterial isolates. A total of 100 samples were obtained; ear infection was slightly elevated in men (58%), but this was not significant. A significantly higher incidence of ear infection was observed in the patients aged 10–19 years (P≤ 0.05). Of the 100 examined ear swab samples, 76 yielded positive culture results, and of these, 61 were axenic and 15 were mixed. Among the 91 retrieved bacterial isolates, Pseudomonas aeruginosa (24/91, 26.3%) and Staphylococcus aureus (21/91, 23%) were the common causative agents of ear infection, while Haemophilus influenzae (2/91, 2.19%) and Staphylococcus hominis (1/91, 1.09%) were less common. Most bacterial isolates showed high sensitivity to imipenem and amikacin (87.9% and 79.1%, respectively; P≤ 0.01), followed by ciprofloxacin and gentamicin (67% and 60.4%, respectively; P≤ 0.05), and low sensitivity to amoxicillin/clavulanic acid and ampicillin (15.3% and 6.6%, respectively). Multidrug resistance was observed in most of the isolates.

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Section: Discussionmentioning

confidence: 99%

Prevalence and Antibiotic Sensitivity Profile of Bacteria in Patients with Ear Infections

Al-Tulaibawi¹,

Aal-Aaboda²,

Al-Qaesy³

2023

J. Pure Appl. Microbiol.

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“…In this study, we investigate the antioxidant, healing, and direct antimicrobial properties of ARAG. To ensure clinical relevance to burn victims, we tested ARAG’s ability to inhibit the growth of bacteria commonly found to colonize burns: K. pneumoniae , P. vulgaris , P. aeruginosa , and S. aureus [ 11 , 12 , 19 , 20 ]. We then compared the efficiency of ARAG to ionized silver to test the in vitro efficacy of ARAG against a simulation of the current standard of care, Mepilex Ag.…”

Section: Introductionmentioning

confidence: 99%

ARAG, an Antioxidant-Rich Gel, Shows Superiority to Mepilex Ag in the Treatment of Deep Partial Thickness Burns without Sacrificing Antimicrobial Efficiency

et al. 2023

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Current treatments for deep tissue burns are limited, and most serve only to enhance hydration or prevent bacterial growth. This leaves burn healing dependent on slow natural processes to debride the wound and reestablish the epidermal and dermal layers of the skin. Infections are well known to destabilize this process through a variety of mechanisms, most notably through increased inflammation and the resulting oxidative stress. In this study, we show that ARAG (an antioxidant-rich antimicrobial gel) can suppress the growth of multiple bacteria commonly found to infect burns (Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa, and Staphylococcus aureus). This inhibition is comparable to that conferred by silver ion release from burn dressings such as Mepilex-Ag. We further show, using a porcine model for deep partial-thickness burns, that ARAG allows for enhanced wound healing over Mepilex-Ag, the current standard of care. Histological findings indicate this is likely due to increased wound debridement and dampening of late inflammatory processes, leading to more balanced physiologic healing. Taken together, these findings show promise for ARAG as a superior alternative to the current standard of care.

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Bacteriological study and its antibiotics susceptibility pattern of Otitis Media in Iraqi patients

Almayali

Al-Kraety

Naji³

et al. 2023

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Otitis media is an acute upper respiratory tract infection-related inflammation of the middle ear and tympanic membrane, frequently affecting children. Typically, a subsequent bacterial infection complicates a viral infection, which ultimately causes the condition. The study aims to study the function of bacterial ear infections and its causes, as well as their resistance to medications, which was the focus of this investigation. The first axis of the research was the identification of bacterial isolates using recognized diagnostic tools, and the second axis was determining the antibiotic's resistance and sensitivity. Patients with otitis media were gathered from Al-Hakim General Hospital and Al-Sadr city hospital in Al-Najaf city between November 2020 and April 2021 for 100 clinical samples. More than 80 samples were found to be infected with bacteria. Bacterial strains found in this investigation are ( 30 ) isolates of Pseudomonas aeruginosa, (20) isolates of Klebsiella spp, (20) isolates of Proteus spp, ( 15 ) isolates of Staphylococcus aureus, (8) isolates Escherichia coli and (7) isolates Enterococcus fecalies. As part of this research, the disk diffusion method was used to assess how sensitive the test was. The results showed that Pseudomonas aeruginosa was resistant to most antibiotics, particularly the penicillin family, cephalosporin, and trimethoprim, with the existence of isolates resistant to meropenem. The investigation results varied for the quinolone, aminoglycoside, and macrolide families. Klebsiella spp. were tested for antibiotic sensitivity and found to be resistant to most antibiotics, particularly those in the penicillin family, cephalosporins, and trimethoprim. Some quinolones, aminoglycosides, and macrolides are also resistant. Proteus spp were resistant to most antibiotics, particularly the penicillin family (except for augmentin, which had some sensitive isolates) and cephalosporin (except for cefdinir and cefepime) had some susceptible isolates) and trimethoprim, in addition to the presence of isolates resistant to meropenem. There is a discrepancy in the examination results for the quinolone family. The aminoglycoside family is also highly resistant. S. aureus isolates were resistant to penicillin (except for augmentin, which some isolates were responsive to), trimethoprim, and quinolones, with the presence of isolates resistant to vancomycin. The macrolide class ( azithromycin) also has a significant resistance level. Escherichia coli is susceptible to meropenem, imipenem, and certain cephalosporin generations. Augmentin, cefepime, cephalothin, meropenem, imipenem, and azithromycin were ineffective against Enterococcus fecal. The conclusion is that Pseudomonas spp has a role in ear infections and the germs Klebsiella spp., Proteus spp., Staphylococcus aureus, Escherichia coli, and Enterococcus fecalies. Penicillin and cephalosporin resistance was seen in the majority of the identified isolates. The existence of isolates of Proteus and Pseudomonas species resistant to meropenem. Vancomycin-resistant strains of Staphylococcus aureus isolates are present. Keywords: Otitis media, Resistance antibiotic, S.aureus, P.aerginosa

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Isolation and Identification of Pathogenic Bacteria Causing Otitis Media in Misan Governorate

Cited by 3 publications

References 47 publications

Prevalence and Antibiotic Sensitivity Profile of Bacteria in Patients with Ear Infections

Prevalence and Antibiotic Sensitivity Profile of Bacteria in Patients with Ear Infections

ARAG, an Antioxidant-Rich Gel, Shows Superiority to Mepilex Ag in the Treatment of Deep Partial Thickness Burns without Sacrificing Antimicrobial Efficiency

Bacteriological study and its antibiotics susceptibility pattern of Otitis Media in Iraqi patients

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