Isolation And Characterization Of Tenuazonic Acid Produced By Alternaria Alternata, A Potential Bioherbicidal Agent For Control Of Lantana Camara

Sanodiya, Bhagwan S.; Thakur, Gulab S.; Baghel, Rakesh Kumar; Pandey, Akhilesh Kumar; Prasad, G. V. R.; Bisen, Prakash S.

doi:10.2478/v10045-010-0023-3

Cited by 19 publications

(15 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Depudecin ( 257 ), an inhibitor of histone deacetylase (HDAC) from A. brassicicola , also showed its antitumor potency [ 8 , 9 ]. Some Alternaria metabolites such as tenuazonic acid ( 15 ), maculosin ( 43 ) and tentoxin ( 53 ) have been studied as the herbicide candidates [ 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Metabolites from Alternaria Fungi and Their Bioactivities

et al. 2013

View full text Add to dashboard Cite

Alternaria is a cosmopolitan fungal genus widely distributing in soil and organic matter. It includes saprophytic, endophytic and pathogenic species. At least 268 metabolites from Alternaria fungi have been reported in the past few decades. They mainly include nitrogen-containing metabolites, steroids, terpenoids, pyranones, quinones, and phenolics. This review aims to briefly summarize the structurally different metabolites produced by Alternaria fungi, as well as their occurrences, biological activities and functions. Some considerations related to synthesis, biosynthesis, production and applications of the metabolites from Alternaria fungi are also discussed.

show abstract

Section: Introductionmentioning

confidence: 99%

Metabolites from Alternaria Fungi and Their Bioactivities

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Previous studies have shown that Alternaria species can produce metabolites with significant phytotoxic properties. For example, tenuazonic acid, maculosin, and tentoxin have been studied as herbicide candidates . Moreover, some Alternaria phytotoxins can affect many plants, regardless of whether they are hosts or non‐hosts of the pathogen .…”

Section: Discussionmentioning

confidence: 99%

Two Phytotoxins Isolated from the Pathogenic Fungus of the Invasive Weed Xanthium italicum

Tang

Huang

Liu

et al. 2020

Chemistry & Biodiversity

View full text Add to dashboard Cite

Alternariol and altenuisol were isolated as the major phytotoxins produced by an Alternaria sp. pathogenic fungus of the invasive weed Xanthium italicum. Altenuisol exhibited stronger phytotoxic effect compared with alternariol. At 10 μg/mL, alternariol and altenuisol promoted root growth of the monocot plant Pennisetum alopecuroides by 11.1 % and 75.2 %, respectively, however, inhibitory activity was triggered by the increase of concentration, with root elongation being suppressed by 35.5 % and 52.0 % with alternariol and altenuisol at 1000 μg/mL, respectively. Alternariol slightly inhibited root length of the dicot plant Medicago sativa at 10-1000 μg/mL, whereas altenuisol stimulated root growth by 51.0 % at 10 μg/mL and inhibited root length by 43.4 % at 200 μg/mL. Alternariol and altenuisol did not exert strong regulatory activity on another dicot plant, Amaranthus retroflexus, when tested concentration was low, however, when the concentration reached 1000 μg/ mL, they reduced root length by 68.1 % and 51.0 %, respectively. Alternariol and altenuisol exerted similar effect on shoot growth of three tested plants but to a lesser extent. It is noteworthy to mention that this is the first report on the phytotoxicity of altenuisol.

show abstract

“…They are allelopathic metabolites of J46. Although tenuazonic acid is a potential bioherbicidal agent (Sanodiya et al 2010), there is no report of an allelopathic effect of vivotoxin II against plants.…”

Section: Discussionmentioning

confidence: 99%

Allelopathy and the active metabolites of the endophytic fungus, Alternaria J46, from Platycladus orientalis

Hao

Yan

Wang

et al. 2015

Weed Biology and Management

View full text Add to dashboard Cite

The endophytic fungus, Alternaria J46, was isolated from the stem of the medicinal plant, Platycladus orientalis. A suspension of Alternaria J46 mycelial segments and the culture filtrates of the fungi exhibited marked seed germination inhibition against the monocot wheat, large crabgrass, bromegrass, rice and barnyardgrass and weak inhibition against the dicot redroot pigweed and morning glory, but it was safe for use on soybean, rape, cucumber, tomato, lettuce and radish crops. It is possible to use J46 culture filtrates in order to prevent monocot weeds in dicot cropland. Three active metabolites were isolated from an extract of the fungus cultures and elucidated as 3-acetyl-5-sec-butyltetramic acid (1, tenuazonic acid), 3-acetyl-5-iso-butyltetramic acid (2, vivotoxin II) and cyclo-(L-leucyl-L-proline) (3). Among these three compounds, compounds 1 and 2 showed significant phytotoxic effects on the seed germination of large crabgrass, while compound 3 exhibited weak activity, and all were safe for lettuce at 100 μg mL −1 . Accordingly, compounds 1 and 2 were the main active metabolites that were responsible for endophytic fungus Alternaria J46's strong seed germination inhibition against monocotyledons.

show abstract

Isolation And Characterization Of Tenuazonic Acid Produced By Alternaria Alternata, A Potential Bioherbicidal Agent For Control Of Lantana Camara

Cited by 19 publications

References 26 publications

Metabolites from Alternaria Fungi and Their Bioactivities

Metabolites from Alternaria Fungi and Their Bioactivities

Two Phytotoxins Isolated from the Pathogenic Fungus of the Invasive Weed Xanthium italicum

Allelopathy and the active metabolites of the endophytic fungus, Alternaria J46, from Platycladus orientalis

Contact Info

Product

Resources

About