Isolation and Characterization of Anthocyanins in Four Varieties of &amp;lt;i&amp;gt;Vigna subterranea&amp;lt;/i&amp;gt; (&amp;lt;i&amp;gt;Fabaceae&amp;lt;/i&amp;gt;)

Mbaiogaou, Abel; Betoloum, Salomon Madjitoloum; Mbaihougadobe, Severin; Naitormbaide, Michel; Héma, Adama; Palé, Éloi

doi:10.4236/ijoc.2022.122009

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Bambara Beans1

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2023

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“…Bambara has antioxidant and anticancer activity tested with HT-29/Caco-2 colon cancer cells in vitro that can reduce and inhibit the proliferation of CRC cells. bambara has the potential for natural therapies to prevent CRC [43].…”

Section: Bambara Beansmentioning

confidence: 99%

Anthocyanin as Colorectal Anticancer: A Brief Review

Siwanahono¹,

Putri²,

Azhar³

2023

IJASRE

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Colorectal Cancer (CRC) is dangerous cancer that causes many cases of death in the world. This cancer spike occurred in 2020 with 1.15 million cases and is expected to increase in 2040 by 1.92 million CRC cancer cases. Some of the most popular drugs used for CRC chemotherapy are 5-Fluorouracil, Oxaliplatin, and Irinotecan. The effects caused by chemotherapy using synthetic drugs are loss of appetite, fatigue, vomiting, numbness, hair loss, and low blood cell count. Anthocyanins are a group of flavonoid compounds and polyphenols with antioxidant, antimutagenic, and anticancer activity that can be developed as CRC anticancer. Anthocyanins do not cause side effects in CRC patients. This article is a review of anthocyanin activity to reduce the risk of colorectal cancer (CRC) in terms of molecular mechanisms, the proliferation ability of cancer cells, and promoting apoptosis of CRC cells.

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Section: Bambara Beansmentioning

confidence: 99%