“…The representative enzyme sequences for each member in the de novo pathway and the corresponding accession numbers are: PRPP synthetase (Arabidopsis thaliana, CAA63552) (Krath et al, 1999), Glutamine-PRPP-amidotransferase (Rattus norvegicus, A46088) (Iwahana et al, 1993), glycinamide ribonucleotide (GAR) synthetase (Arabidopsis thaliana, P52420) (Schnorr, et al, 1994), GAR transformylase (Arabidopsis thaliana, P52422) (Schnorr, et al, 1994), Formylglycinamide ribonucleotide (FGAM) synthetase (Glycine max, AAF21596, unpublished direct submission), 5-aminoimidazole ribonucleotide (AIR) synthetase (Arabidopsis thaliana, Q05728) (Senecoff and Meagher, 1993), AIR carboxylase (Arabidopsis thaliana, T02535, unpublished direct submission), 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide (SAICAR) synthetase (Arabidopsis thaliana, P38025, unpublished direct submission), adenylosuccinate lyase (Leishmania major, CAC22697) (Ivens et al 1998), with AICAR transformylase and IMP cyclohydrolase bifunctional enzymes (Gallus gallus, P31335) (Ni et al, 1991).…”