Isolated Trigeminal Neuropathy a Report of 16 Cases

Trigeminal neuropathy with nasal ulceration: report of two cases and one necropsy.

“…In a previous paper on isolated trigeminal neuropathy (Spillane and Wells, 1959) one of us described a patient with total bilateral trigeminal loss accompanied by progressive ulceration of her nose (case 15). We now wish to report the subsequent evolution of her condition and postmortem findings which we believe to be unique.…”

Common Neuropathic Itch Syndromes

“…Central lesions, most often vertebrobasilar stroke, are said to cause about 1/5 of cases of TTS (29). Central itch has also been described in multiple sclerosis (30,31), tumors within and immediately outside the brain (32,33), and infections and autoimmune disorders (34), as well as other conditions (29).…”

Neurophysiological assessment of craniofacial pain

“…Trigeminal nerve dysfunction caused by peripheral neuropathies is usually clinically unimportant and rarely painful [39]. ISTN (i.e., not associated with systemic neuropathy) is a rare clinical condition [40]. Several studies described an association between chronic trigeminal sensory neuropathy and connective tissue diseases [41].…”

“…In patients with ISTN, sensory loss develops gradually; first, it is usually localised in the perioral region on one side and then extends, over a period of months or a few years, to the other side, the intraoral mucosa and the tongue, and subsequently the whole face. Pain is a relatively common symptom; it is more often constant, and usually described as burning or aching [40,41]. In the earlier stage of disease, whereas the masseter inhibitory reflex may be abnormal, the blink reflex may be normal.…”