Trigeminal neuropathy with nasal ulceration: report of two cases and one necropsy.

Spillane, J. D.; Urich, H.

doi:10.1136/jnnp.39.2.105

Cited by 27 publications

(22 citation statements)

References 21 publications

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“…6 Case reports of involvement of the central nervous system (CNS) suggest additional interesting aetiologies, such as TTS occurrence after damage caused by amyloid deposits in CNS and the trigeminal nerve. 8 Thus, the literature suggests that the trigeminal lesion is a prerequisite, but not a guarantee, of TTS development. The actual physical mechanism of ulceration is believed to be traumatic secondary to paresthesia.…”

Section: Epidemiologymentioning

confidence: 99%

“…Ulcer formation is triggered by an unconscious self-mutilation in response to a sensation of itching and burning. [8][9][10] For a time, a trophic theory was proposed to explain the ulcer formations. 10 According to this theory, a CNS disorder was at play, involving the alteration of certain, as yet undiscovered, trophic factor secretions, rendering them unable to play their role in the maintenance of facial skin.…”

Section: Epidemiologymentioning

confidence: 99%

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Trigeminal trophic syndrome

Rashid

Khachemoune

2007

Acad Dermatol Venereol

136

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Trigeminal trophic syndrome (TTS) is a rare cause of facial ulceration, which is believed to develop after insult to the trigeminal ganglia or other parts of the peripheral/central nervous system in the trigeminal pathway. The pathogenesis of TTS is poorly understood. Developing a better understanding of TTS will allow early recognition and improved treatment. Although the ulcers develop predominantly on the ala nasi, the literature on ulcer locations is limited. In this article, we review the epidemiologic aspects of TTS, expand on our knowledge of the anatomic location of the ulcers, and discuss current theories for its aetiology and briefly review the approaches to its management.

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Section: Epidemiologymentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

Trigeminal trophic syndrome

Rashid

Khachemoune

2007

Acad Dermatol Venereol

136

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“…Die Entstehung eines NTS nach Alkorationen, bis zum Verlust der Nase, fanden sich nach einer beidseitigen Ausschaltung des Ganglion Gasseri bzw. bei beidseitiger Trigeminusneuropathie [19,25]. Erleiden junge Patienten diese Ulzerationen, so ist eine kongenitale Trigeminushypoplasie zu bedenken, welche auch familiär gehäuft auftreten kann [10,17].…”

Section: Abb1 ᭣ Mrt-bild (Koronar T1-gewichtet) Mit Signalangehobenunclassified

Trigeminotrophe Ulzeration des Nasenflügels bei Wallenberg-Syndrom

Schommer

Weiss²,

Kiehl³

et al. 2000

Der Hautarzt

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A patient developed a trophic ulceration of the nose after an acute bulbar ischemia with infarction of the right trigeminal nuclei. Neurologic examination showed symptoms of a Wallenberg syndrome including ipsilateral hyp- and paresthesia of the second trigeminal branch and disturbed sensibility and temperature sense on the contralateral half of the body. The right ala nasi showed the characteristic sickle-shaped defect (ulcération en arc). The differential diagnosis and therapeutic approaches are discussed.

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“…3 The most common etiological factor (75% of cases) is trigeminal surgical ablation by rhizotomy or alcohol injection in the gasserian ganglion for the treatment of trigeminal neuralgia. Less common etiological factors include vertebrobasilar insufficiency,5 syringobulbia, acoustic neuroma,6 and postencephalitic parkinsonism.…”

Section: Introductionmentioning

confidence: 99%