Isolated bulbar palsy after SARS-CoV-2 infection

Todisco, Massimiliano; Alfonsi, Enrico; Arceri, Sebastiano; Bertino, Giulia; Robotti, Carlo; Albergati, Michele; Gastaldi, Matteo; Tassorelli, Cristina; Cosentino, Giuseppe

doi:10.1016/s1474-4422(21)00025-9

Cited by 12 publications

(9 citation statements)

References 5 publications

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“…Pre-COVID-19 ML studies demonstrated the relevance of cough samples for detecting multiple respiratory conditions [86,87]. However, it is conceivable that proper speech tasks may provide additional valuable features for MLVA, potentially even more representative of the multifaceted interactions between phonatory subsystems [36,52] and their impairment in COVID-19 [53][54][55]57]. Indeed, the vowel task proved higher accuracy and AUC values than cough when discriminating between groups P and H and between groups P and R, demonstrating lower performances only when discriminating between groups R and H, thus confirming that speech tasks may have at least similar informative contents.…”

Section: Discussionmentioning

confidence: 99%

“…Thirdly, to the best of our knowledge, only two studies included vocal samples other than cough in the analyses [50,51]. Specifically, in our opinion, proper speech tasks could provide valuable additional features for MLVA implementation, in reason of the complex interactions between voice-production subsystems [36,52] and their peculiar impairments in COVID-19 [53][54][55]57]. Lastly, no ML study enrolled recovered COVID-19 patients to date, even though they may represent a crucial population for multiple reasons, including potential residual viral spreading [58][59][60] and severe long-term disabilities [61][62][63].…”

Section: Deep Learning (Dl) Especially Based On Convolutional Neural Network (Cnn) Applied Tomentioning

confidence: 99%

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Machine Learning-based Voice Assessment for the Detection of Positive and Recovered COVID-19 Patients

et al. 2024

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Discussionmentioning

confidence: 99%

Section: Deep Learning (Dl) Especially Based On Convolutional Neural Network (Cnn) Applied Tomentioning

confidence: 99%

Machine Learning-based Voice Assessment for the Detection of Positive and Recovered COVID-19 Patients

et al. 2024

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“…From the early days of the pandemic, reports of neurologic manifestations, such as Guillain-Barré syndrome, anosmia, and encephalitis [9][10][11][12], were common, with neurologic manifestations being reported to be occurring in more than 80% of patients affected by COVID-19 according to one study [13]. With the progression of time, many newer neurologic complications were reported, such as the involvement of the cranial nerves [14]. These studies show that SARS-CoV-2 has the propensity to attack nerves all over the body and can present with a constellation of disease presentations.…”

Section: Discussionmentioning

confidence: 99%

Unilateral Diaphragmatic Paralysis in a Patient With COVID-19 Pneumonia

Shahid¹,

Nasir²,

Shahid³

et al. 2021

Cureus

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is best known for causing febrile pneumonia with lung parenchymal involvement. However, that is often not the only disease presentation, as many studies have shown that coronavirus disease 2019 (COVID-19) can present with other complications involving the cardiovascular and neurologic systems. Here, we report a case of COVID-19 pneumonia presenting with a peculiar finding of unilateral diaphragmatic paralysis. The patient presented with dyspnea requiring oxygen support via a nasal cannula. He was managed with the hospital's COVID-19 treatment protocols and clinically improved within 14 days of admission. This case helps shine some light on the neuroinvasive potential of SARS-CoV-2.

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“…Lower motor neuron facial palsy may be due to direct (viral) or indirect (immune-mediated) effects of SARS-CoV-2 virus. 19 Direct neuroinvasion may occur by the virus entering the cell using ACE-2 receptors. 20 On the other hand, in indirect mechanism, SARS-CoV-2 infection triggers the immune system, stimulating production of a plethora of antibodies.…”

Section: Discussionmentioning

confidence: 99%

Otoneurological presentations of COVID-19

2021

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COVID-19 usually begins with respiratory symptoms but may also cause neurological disturbances by direct (viral invasion) or indirect (immune-mediated) mechanism. Common neurological injury described in the literature include infectious toxic encephalopathy, viral encephalitis and Guillain-Barré syndrome. We present two cases diagnosed with COVID-19 who presented with isolated neurological deficit along facial nerve and vestibular nerve. Both recovered with medical management and rehabilitative exercises. Isolated neurological impairment in otorhinolaryngological practice may be the primary presentation or delayed feature of COVID-19.

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Isolated bulbar palsy after SARS-CoV-2 infection

Cited by 12 publications

References 5 publications

Machine Learning-based Voice Assessment for the Detection of Positive and Recovered COVID-19 Patients

Machine Learning-based Voice Assessment for the Detection of Positive and Recovered COVID-19 Patients

Unilateral Diaphragmatic Paralysis in a Patient With COVID-19 Pneumonia

Otoneurological presentations of COVID-19

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