Isolasi dan Identifikasi Steroid dari Ekstrak  N-Heksana Daun Afrika (Vernonia amygdalina Del.)

Mashunah, Evi; Erwin, Erwin; Sitorus, Saibun

doi:10.22487/kovalen.2020.v6.i1.15032

Cited by 5 publications

(5 citation statements)

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“…Steroid diketahui berinteraksi dengan membran sel fosfolipid, yang diketahui permeabel terhadap senyawa lipofilik. Interaksi tersebut dapat mengakibatkan penurunan integritas membran serta perubahan morfologi membran sel yang keduanya dapat menyebabkan kerapuhan dan lisis sel (Mashunah & Sitorus, 2020) Besarnya aktivitas antibakteri ekstrak terhadap bakteri uji juga dipengaruhi oleh konsentrasi ekstrak. Berdasarkan data yang disajikan sebelumnya, dapat disimpulkan bahwa sejauh mana ekstrak menghambat pertumbuhan bakteri sebanding dengan konsentrasi ekstrak.…”

Section: Tabel 3 Kategori Diameter Zona Hambat Bakteriunclassified

Uji Aktivitas Antibakteri Ekstrak Daun Karenda (Carissa carandas Linn.) Terhadap Bakteri Propionibacterium acne dan Staphylococcus epidermidis

Kaban,

Nasri,

Syahputra

et al. 2023

jharma

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Karenda leaves contain flavonoids, steroids or triterpenoids, saponins, and tannins that act as antimicrobial compounds. The aim of the study was to determine the antibacterial activity of the ethanol extract of Karenda leaves against several acne-causing bacteria. The research method involved characterizing the simplicia of karenda leaves and extract preparation by maceration using 96% ethanol as a solvent. and test the antibacterial activity of the ethanol extract of Karenda leaves using the agar diffusion method. The bacteria used were Propionibacterium acnes and Staphylococcus epidermis. The extract concentrations used were 300, 150, 125, 100, 75, 50, 25, and 5 mg/mL. Based on tests carried out by the ethanol extract of karenda leaves, the diameters of the inhibition zones were 7.2 ± 0.12 respectively; 7.8±0.10; 9.7±0.15; 11.23±0.25; 12.43±0.06; 13.57±0.06; 14.20±0.10; 16.47 ± 0.21 for Propionibacterium acne and 8.17 ± 0.06; 9.37 ± 0.15; 9.80 ± 0.10; 10.73 ± 0.15; 11.27±0.12; 12.43±0.06; 13.77±0.06; 15.47 ± 0.12 for Staphylococcus epidermis. he test results proved that 300 mg/mL was the best concentration for inhibiting the growth of Propionibacterium acnes and Staphylococcus epidermis bacteria.

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Section: Tabel 3 Kategori Diameter Zona Hambat Bakteriunclassified

Uji Aktivitas Antibakteri Ekstrak Daun Karenda (Carissa carandas Linn.) Terhadap Bakteri Propionibacterium acne dan Staphylococcus epidermidis

Kaban,

Nasri,

Syahputra

et al. 2023

jharma

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“…The filtrate was evaporated, and the remaining liquid was mixed with Liebermann-Burchad reagent through the cup walls. If a red hue forms and then transforms to a greenish blue, it is considered positive for triterpenoids or steroids [12], [13].…”

Section: Identification Of Steroids/triterpenoidsmentioning

confidence: 99%

Phytochemical Screening And Antibacterial Activity Of The Ethanol Extract Of Putri Malu (Mimosa Pudica Linn.) Leaves Combined With Klanceng Honey Against Staphylococcus Aureus Bacteria

Dalimunte,

Arianto,

Salim

2023

International Journal of Science, Technology & Management

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Mimosa pudica Linn. Leave and honey have been known to have antibacterial activity. The combination of the two is very beneficial as an antibacterial because the hydrogen peroxide content in honey and the flavonoid metabolite compounds in Putri Malu provide a synergistic effect as an antibacterial. The aim of this research was to determine the activity of the ethanol extract of Putri Malu leaves combined with Klanceng honey using the disc diffusion method against Staphylococcus aureus bacteria. The results showed that the resulting extract was thick and blackish-green in colour, with a yield of 25.6%. The results of the phytochemical screening test showed that Putri Malu extract contains alkaloids, flavonoids, glycosides, saponins, and tannins. Characterization results showed that the water content of the extract was 7.28 ± 0.05, water-soluble essence content was 16.03 ± 0.08, ethanol-soluble essence content was 19.65 ± 0.01, total ash content was 4.70 ± 0.00, and essence content acid soluble was 0.17±0.02. Antibacterial testing showed that the best ratio of Putri Malu leaf extract to honey to inhibit Staphylococcus aureus was 9:1, with an inhibitory value of 13.60 ± 0.40 mm. In conclusion, the combination of Putri Malu leaf extract with honey strongly inhibits the growth of Staphylococcus aureus bacteria.

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“…It is said to be positive for triterpenoids or steroids if a red color is formed that turns blue-green. 12,13 Harahap ND et al Int J Basic Clin Pharmacol. 2024 Jan;13( 1…”

Section: Identification Of Steroid/triterpenoidsmentioning

confidence: 99%

Antibacterial activity of tekelan leaf ethanol extract (Chromolaena odorata (L.) R. M. King and H. Rob) against of Staphylococcus aureus bacteria

Harahap,

Dalimunthe,

Bangun

2023

Int J Basic Clin Pharmacol

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Background: Indonesia is a tropical country, so the prevalence of infectious diseases caused by bacteria still remains high. On the other hand, the intense use of antibacterial agent in Indonesia causes a tendency for bacterial resistance to existing antibacterial drugs. One of the herbal plants that is widely used by some people is tekelan leaves. The purpose of this study was to determine the activity of an ethanol extract of tekelan leaves on the growth of Staphylococcus aureus bacteria. Methods: Simplisia of tekelan leaves was tested for secondary metabolites and simplisa characterization testing. Antibacterial activity testing is carried out by the disc paper method, where the disc paper is immersed in the test solution with a comparison of the test concentration. Results: The results of phytochemical screening show that the secondary metabolites of tekelan leaves are alkaloids, flavonoids, steroids/triterpenoids, tannins, and glycosides. The results of the characterization of simplisia moisture content are 7.99%, water-soluble juice content is 13.29%, ethanol-soluble juice content is 12.18%, total ash content is 7.45%, and insoluble acid ash content is 0.92%. The observation of the antibacterial activity of the ethanol extract of tekelan leaves was carried out by the disc diffusion method. The test results showed that the ethanol extract of tekelan leaves was categorized as moderate at concentrations of 1% and 2% and as strong at concentrations of 4%, 5%, 10%, 20%, 40%, 60%, 80%, and 100%. The conclusion of this study is that ethanol extract had activity to inhibit the growth of Staphylococcus aureus and the MIC value obtained 0.7%. Conclusions: The conclusion of this study is that ethanol extract had activity to inhibit the growth of Staphylococcus aureus.

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Isolasi dan Identifikasi Steroid dari Ekstrak N-Heksana Daun Afrika (Vernonia amygdalina Del.)

Cited by 5 publications

References 0 publications

Uji Aktivitas Antibakteri Ekstrak Daun Karenda (Carissa carandas Linn.) Terhadap Bakteri Propionibacterium acne dan Staphylococcus epidermidis

Uji Aktivitas Antibakteri Ekstrak Daun Karenda (Carissa carandas Linn.) Terhadap Bakteri Propionibacterium acne dan Staphylococcus epidermidis

Phytochemical Screening And Antibacterial Activity Of The Ethanol Extract Of Putri Malu (Mimosa Pudica Linn.) Leaves Combined With Klanceng Honey Against Staphylococcus Aureus Bacteria

Antibacterial activity of tekelan leaf ethanol extract (Chromolaena odorata (L.) R. M. King and H. Rob) against of Staphylococcus aureus bacteria

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