Ischemic stroke in young adults. II. Analysis of risk factors in the etiological subgroups

Matías-Guiu, J; Alvarez, J.; Insa, R; Moltò, J. M.; Martín, R.; Codina, A; Martínez-Vázquez, J M

doi:10.1111/j.1600-0404.1990.tb01561.x

Cited by 17 publications

(3 citation statements)

References 20 publications

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“…The relationship between diabetes mellitus and stroke has been well documented in general populations [18–21], but not yet in young adults. The studies performed to analyse the effect of diabetes in the formation of an ischemic stroke didn't bring a real scientific proof to its involvement but it is indeed a highly suspected risk factor [22–24], our study found diabetes to be responsive of 13% of all cases, finally; approximatively 18% of our patients had a pre-existing heart disease, this situation is in agreement with the findings of general population studies that suggest embolic cardiopathies to be a high risk factor of stroke [25, 26]. The conclusions and recommendation that we should perform in order to improve the prevention of stroke among the young adults are; a more efficient and an early diagnosis of all this risk factors by the information and education of our population who is still very far from establishing the relationship between this factors and stroke.…”

Section: Discussionmentioning

confidence: 99%

Stroke in young adults: about 128 cases

Chraa¹,

Louhab²,

Kissani³

2014

Pan Afr Med J

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Ischemic stroke is rare in young adults, but it is genuinely a serious situation giving the fact that it touch a very active part of our society. We report a series of 128 cases. The purpose is to analyze the risk factors, etiologies and outcomes of ischemic stroke in young adults in Marrakesh. Retrospective study performed at the Neurology department Mohammed VI universitary hospital in Marrakesh interesting 128 patients. The diagnosis of ischemic stroke was assessed through clinical and radiological confrontation. Results: The age of our patients varied from 18 to 45 years old, 76 males and 52 females giving a male: female ratio of 1:46. Hypertension was the first risk factor involved with 63 (49.2%) cases, followed by smoking with 52 (40.6%) patients. The causes of ischemic stroke were characterized by the predominance of the cardio embolic origin with 43 (33.5%) cases, the existence of 14 (11%) cases of syphilitic arthritis, and the 52 (40.6%) cases of unknown etiologies. The authors stress the difficulties faced on supporting ischemic stroke in southern Morocco in particular when concerned by the etiological finding and the rehabilitation after the acute phase of the stroke. Our study points out the high incidence of embolic heart disease in our context. The lack of neurologists, low coverage of the population and the underestimation by physicians are factors that can explain why ischemic stroke remain undiagnosed.

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Section: Discussionmentioning

confidence: 99%

Stroke in young adults: about 128 cases

Chraa¹,

Louhab²,

Kissani³

2014

Pan Afr Med J

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“…Etiology and risk factors [45,80,82,98,[104][105][106][107][108][109][110][111][112][113][114][115][116][117] FHS was consistently associated with small vessel disease [80,82,[104][105][106][107][108] and large vessel disease [80,98,[105][106][107][108], but not with cardioembolic etiology [45,116,117].…”

Section: Parameter Publications Correlationmentioning

confidence: 99%

“…With regards to stroke etiology, authors consistently reported an association of FHS with small vessel disease [80,82,[104][105][106][107][108], subclinical lacunes [109,110], intracranial artery stenosis [111][112][113][114][115] and large vessel disease [80,98,[105][106][107][108], but not with cardioembolic stroke [45,116,117]. One paper found that FHS was related to lacunar stroke in older subjects and cryptogenic etiology in the younger [118].…”

Section: Type Of Stroke Etiology and Interaction With Risk Factorsmentioning

confidence: 99%

Family history of stroke – a useful clue for the primary care physician and stroke neurologist: a narrative review

Błaż¹,

Sarzyńska‐Długosz²

2023

ppn

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Purpose:The heritability of ischemic stroke is a complex mechanism, involving the contribution of genetic traits and environmental factors, which is why in everyday practice clinicians often rely on the broad term "family history of stroke", defined as the case of any first-degree relative who has had a stroke. The aim of this review is to update the available data regarding family history of stroke in primary and secondary stroke prevention by searching the electronic Scopus database for the phrase TITLE-ABS-KEY ("family history" AND "stroke"). Views: A total of 140 articles met the pre-specified criteria and were included in the review. The prevalence of family history of stroke ranged from 37% in stroke-free individuals to 52% in patients with ischemic stroke. In primary prevention, family history of stroke was associated with increased risk of stroke, transient ischemic attack, stroke risk factors and stroke-like symptoms. In patients with ischemic stroke, it was more often associated with small-and large-vessel disease, though not with a cardioembolic etiology. Family history of stroke did not influence long-term functional outcomes after rehabilitation. In young stroke victims, it was related to symptom severity and the risk of a second stroke. Conclusions: Consideration of family history of stroke in everyday practice may carry useful information both for primary care physicians and stroke neurologists.

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Family history: A comprehensive genetic risk assessment method for the chronic conditions of adulthood

et al. 1997

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Targeting individuals with increased risk for common, chronic disease can improve the efficiency and efficacy of preventive efforts by improving the predictability of screening tests and participant compliance. Individuals with the greatest risk for these disorders are those with a genetic susceptibility. The purpose of this study was to determine the feasibility of using a single, comprehensive family history as a method for stratifying risk for many preventable, common genetic disorders. Family histories obtained in a prenatal diagnostic clinic were reviewed regarding cardiovascular diseases, diabetes and several cancers; 42.5% of individuals reported a family history for at least one of the disorders under study. Familial coronary artery disease was most commonly reported (29% of participants), followed by noninsulin-dependent diabetes (14%). Qualitative characterization of disease susceptibility was also accomplished using family history data. For example, occurrence of different cancers within pedigrees was suggestive of familial cancer syndromes, and clustering of noninsulin-dependent diabetes and cardiovascular disease suggested an insulin resistance syndrome. Depending on the specific disease, 5 to 15% of at-risk individuals had a moderately increased risk (2 to 5 times the population risk), and approximately 1 to 10% had a high risk (absolute risks approaching 50%). Family history reports of common, chronic disease are prevalent among the population at large, and collection and interpretation of comprehensive family history data is a feasible, initial method for risk stratification for many preventable, chronic conditions. These findings may have important implications for disease prevention and management.

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Ischemic stroke in young adults. II. Analysis of risk factors in the etiological subgroups

Cited by 17 publications

References 20 publications

Stroke in young adults: about 128 cases

Stroke in young adults: about 128 cases

Family history of stroke – a useful clue for the primary care physician and stroke neurologist: a narrative review

Family history: A comprehensive genetic risk assessment method for the chronic conditions of adulthood

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