Ischemic stroke in neurosarcoidosis: A retrospective cohort analysis

Hutto, Spencer K.; Kyle, Kevin; Balaban, Denis; Martinez‐Lage, Maria; Venna, Nagagopal

doi:10.1016/j.msard.2022.104227

Cited by 3 publications

(3 citation statements)

References 29 publications

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“…The presence of perivascular enhancement (Figure 4D) is noted to increase the incidence of cerebrovascular events [30]. Hutto et al assessed Small vessel involvement of lenticulostriate and pontine perforators occurred in 10/11 (90.9%), with leptomeningeal enhancement being present in all these cases [34].…”

Section: Vasculitismentioning

confidence: 96%

“…assessed 11 neurosarcoidosis patients who manifested ischaemic stroke, with 4 presenting with initial ischaemic stroke and 7 experiencing strokes during the course of the disease. Small vessel involvement of lenticulostriate and pontine perforators occurred in 10/11 (90.9%), with leptomeningeal enhancement being present in all these cases [ 34 ]. Another mechanism of stroke can be due to sarcoid cardiomyopathy, causing an embolic phenomenon [ 31 ].…”

Section: Imaging Findingsmentioning

confidence: 99%

“…Concurrent brain involvement can be seen in up to 70% of cases [32,33]. Several patterns of myelitis have been described on MRI, with longitudinally extensive transverse myelitis being the commonest, followed by short tumefactive myelitis, leptomeningeal enhancement, and anterior myelitis [34].…”

Section: Spinal Involvementmentioning

confidence: 99%

See 2 more Smart Citations

Insights into neurosarcoidosis: an imaging perspective

Cicilet,

Reddy K,

Kancharla

2023

Pol J Radiol

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Neurosarcoidosis is a complex and multifaceted inflammatory disorder affecting the nervous system. The disease, characterized by non-caseating granulomas, primarily involves the central and peripheral nervous systems. Neurological manifestations vary widely and can include cranial nerve palsies, meningeal involvement, parenchymal lesions, hydrocephalus, and more. Diagnosis remains challenging due to the lack of specific imaging features, necessitating a combination of clinical evaluation, cerebrospinal fluid analysis, imaging studies, and sometimes tissue biopsy. This review article underscores the importance of the identification of various imaging features to mitigate the mortality and morbidity associated with neurosarcoidosis.

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Section: Vasculitismentioning

confidence: 96%

Section: Imaging Findingsmentioning

confidence: 99%