Ischemia Time and Liver Transplantation, Today

Maggi, U.; Fornoni, G.; Centonze, Leonardo; Melada, E.; Conte, G.; Rossi, G.

doi:10.1016/j.transproceed.2014.07.040

Cited by 10 publications

(10 citation statements)

References 9 publications

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“…Regarding the risks related to transplantation logistics, the surgical time and the time between donor asystole and aortic clamping were described in two articles 9,22 . A study by Taner In this technique, the portal vein is declamped while…”

Section: Resultsmentioning

confidence: 99%

“…The underlying disease (viral C cirrhosis) was found to cause graft failure in two articles 3,23 . We identified the following risk factors in just one article: use of the anesthetic propofol appearing as increased risk for EGD 2 ; consumption of fresh frozen plasma >30IU 9 ;…”

Section: Resultsmentioning

confidence: 99%

“…Regarding the risks related to the graft, we found: cold shemia time (CIT) >10 hours in four articles 3,9,13,19 , since time below this parameter is considered safe for graft quality. A prospective study of great relevance showed that this factor associated with female gander, donor age >60 years, and infusion of more than 30 fresh frozen plasma units were statistically significant predictors of graft PNF 9 .…”

Section: Resultsmentioning

confidence: 99%

“…Liver dysfunction is characterized by the presence of at least one of the variables: bilirubin =10mg/ml, International Normalized Ratio (INR) =1.6 during the first seven postoperative days, and aminotransferases >2000IU/l in the first week of the postoperative period. Early graft dysfunction (EGD) is described as early malfunction, graft hypofunction, marginal function or delayed function [7][8][9][10] . Its incidence occurs in about 8% to 24.7% of patients 11,12 .…”

Section: Review Articlementioning

confidence: 99%

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Disfunção e não função primária do enxerto hepático: revisão integrativa.

Salviano

Lima

Tonelli

et al. 2019

Rev. Col. Bras. Cir.

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RESUMO Evitar mortes na fila de espera por um órgão não é mais o único foco de atenção das equipes de transplantação. As pesquisas e cuidados na prática clínica têm sido cada vez mais voltados para o funcionamento do enxerto pós-implante. O objetivo desse estudo foi identificar a nomenclatura utilizada na literatura para disfunção e não função de um enxerto hepático, bem como, investigar as incidências e fatores de risco. Trata-se de uma revisão integrativa da literatura de publicações na íntegra em português, inglês e espanhol, entre 2012 e 2016, nas bases: CINAHL, MEDLINE, Cochrane, LILACS, BDENF, IBECS, EMBASE e Web of Science. Foram selecionados 14 estudos em que se identificou incidências variando entre 7% e 27% e a nomenclatura utilizada para descrever o evento foi mau funcionamento inicial, hipofunção do enxerto, função marginal ou retardo na função. Foram encontradas incidências de não função primária do enxerto hepático entre 1,4% e 8,4% dos pacientes e a nomenclatura usada para descrever o evento foi disfunção precoce ou perda do enxerto. Os fatores de risco encontrados são relacionados às variáveis do doador, receptor, enxerto e logística do transplante. Conclui-se que o conhecimento das diferentes nomenclaturas empregadas na literatura, das incidências da disfunção e não função primária e seus fatores de risco são fundamentais para qualificar as intervenções de controle dos eventos na perspectiva de melhorar a sobrevida do paciente pós-transplante hepático.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Review Articlementioning

confidence: 99%

See 2 more Smart Citations

Disfunção e não função primária do enxerto hepático: revisão integrativa.

Salviano

Lima

Tonelli

et al. 2019

Rev. Col. Bras. Cir.

View full text Add to dashboard Cite

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“…It is also associated with higher incidences of Primary Non-Function (PNF) [27] in DDLT. The positive predictive value of PNF after a DDLT based on a deceased donor liver biopsy can be as high as 90% [28], therefore transplant centers when accepting donor livers>30% macrosteatosis on liver biopsy are cautious, and control other variables that can jeopardize the outcomes, like cold ischemic time and warm ischemic time [29]. But, such detailed causal relationship of hepatic steatosis with PNF has not been well studied in LDLT.…”

Section: Bmi and Macrosteatosismentioning

confidence: 99%

Trends and the Current Status of Living Donor Liver Transplant

Batra¹,

Mulligan²

2018

Liver Research and Clinical Management

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The need for liver transplant and its timely nature are both equally vital for a patient with end stage liver disease. But the ever-growing need for liver transplant across the entire world threatens the two reasons that justify its very existence. The popularity of living donor liver transplant has met great enthusiasm amongst the transplant physicians and surgeons, as it is timely, and also yields superior survival benefit as compared to a deceased donor liver transplant. Living donor liver transplant has been constantly adapting to meet the needs of patients and the expanding wait list. The need for a living donor liver transplant is not the same amongst the various parts of the world, because the population and the disease burden is different. We looked at the trend of living donor liver transplant across the world and also the change in practices over time including a glimpse of what lies ahead for the next decades.

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