Isatin‐SO₃H coated on amino propyl modified magnetic nanoparticles (Fe₃O₄@APTES@isatin‐SO₃H) as a recyclable magnetic nanoparticle for the simple and rapid synthesis of pyrano[2,3‐d] pyrimidines derivatives

Abstract

Isatin‐SO3H coated on amino propyl modified magnetic nanoparticles (Fe3O4@APTES@isatin‐SO3H) is found to be a novel, efficient, and reusable magnetic nanocatalyst, and characterized by FT‐IR, SEM, TEM, XRD, EDX, VSM, and TGA analysis. The magnetic nanocatalyst demonstrated outstanding performance in synthesis of pyrano[2,3‐d] pyrimidines derivatives via one‐pot three‐component reaction of various aromatic aldehydes 1, malononitrile 2, and barbituric acid 3 under reflux conditions in mixture of H2O:EtOH (1:1) as solvent. Easy workup procedure, short reaction time, high yield, simple preparation and easy recovery of the catalyst, mild reaction conditions are some advantages of this work.

Synthesis and characterization of Fe3O4@THAM‐SO3H as a highly reusable nanocatalyst and its application for the synthesis of dihydropyrano[2,3‐c]pyrazole derivatives

“…The spectrum of Fe 3 O 4 @THAM‐SO 3 H (Figure b ) shows some bands in 1000–1250 cm −1 which are attributed to the absorption S‐O and S=O stretching bands of ‐SO 3 H moiety on Fe 3 O 4 @THAM‐SO 3 H surface. In addition, the peak at 3405 cm −1 in the spectrum of Fe 3 O 4 @THAM‐SO 3 H was probably attributed to the ‐SO 2 ‐OH groups, which is overlapped by the Fe–OH stretching vibration …”

“…In addition, the peak at 3405 cm −1 in the spectrum of Fe 3 O 4 @THAM-SO 3 H was probably attributed to the -SO 2 -OH groups, which is overlapped by the Fe-OH stretching vibration. [21] The thermal stability of Fe 3 O 4 @THAM-SO 3 H nanoparticles was studied by TG/DTG analysis in the decomposition area of 0-600 C with a heating rate of 10 C per minute under nitrogen atmosphere ( Figure 7). As can be seen, Fe 3 O 4 @THAM-SO 3 H nanoparticles displayed four weight-loss steps.…”

“…[16][17][18][19][20] As a review of previous studies, many methods have been reported for sulfuric acid coupling as an acidic group on magnetic nanoparticles. Among them, Fe 3 O 4 @APTES@isatin-SO 3 H, [21] CoFe 2 O 4 @SiO 2 -SO 3 H, [22] Fe 3 O 4 @BNPs@SiO 2 -SO 3 H, [23] Fe 3 O 4 @zeolite-SO 3 H, [24] Fe 3-x TixO 4 -SO 3 H [25] and Fe 3 O 4 @GO-naphthalene-SO 3 H [26] are examples of catalysts.…”

Fe3O4@APTES@isatin-SO3H as heterogeneous and efficient catalyst for the synthesis of quinoxaline derivatives

“…Magnetite Fe 3 O 4 @APTES@isatin-SO 3 H was prepared according to the literature procedure and fully characterized by EDX, FT-IR, XRD, VSM, TEM, SEM, and TGA techniques (Please see supporting information [35].…”

Synthesis of bioactive magnetic nanoparticles spiro[indoline‐3,4′‐[1,3]dithiine]@Ni (NO3)2 supported on Fe3O4@SiO2@CPS as reusable nanocatalyst for the synthesis of functionalized 3,4‐dihydro‐2H‐pyran

“…Although homogeneous catalysts increase speed and efficiency of these reactions more than heterogeneous catalysts, their separation as well as enhanced number of steps make them costlier to be used . There are a large number of reports on the applications of magnetic nanoparticles (MNPs) in industry and chemistry . Fe 3 O 4 coated as a magnet core and supported by organic compounds has found a special place in the synthesis of heterogeneous magnetic nanocatalysts as such many relevant studies have been carried out in this regard .…”