Is Tissue Oxygen Tension during Esophagectomy a Predictor of Esophagogastric Anastomotic Healing?

Jacobi, C. A.; Zieren, H. U.; Zieren, Jürgen; Müller, J. M.

doi:10.1006/jsre.1997.5239

Cited by 35 publications

(25 citation statements)

References 9 publications

(2 reference statements)

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“…Conversely, in a study by Jacobi et al, no decrease of the submucosal PtO2 was seen in patients with anastomotic insufficiency after esophageal resections. Even increased PtO2 values were observed in the anastomotic leakage group [17] . These controversial findings have led to doubts about the role of impaired tissue oxygenation in anastomotic healing.…”

Section: Polarographic Measurement Of Oxygen Tensionmentioning

confidence: 86%

How to assess intestinal viability during surgery: A review of techniques

Urbanavičius

Pattyn²,

Putte³

et al. 2011

WJGS

188

156

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Objective and quantitative intraoperative methods of bowel viability assessment are essential in gastrointestinal surgery. Exact determination of the borderline of the viable bowel with the help of an objective test could result in a decrease of postoperative ischemic complications. An accurate, reproducible and cost effective method is desirable in every operating theater dealing with abdominal operations. Numerous techniques assessing various parameters of intestinal viability are described by the studies. However, there is no consensus about their clinical use. To evaluate the available methods, a systematic search of the English literature was performed. Virtues and drawbacks of the techniques and possibilities of clinical application are reviewed. Valuable parameters related to postoperative intestinal anastomotic or stoma complications are analyzed. Important issues in the measurement and interpretation of bowel viability are discussed. To date, only a few methods are applicable in surgical practice.Further studies are needed to determine the limiting values of intestinal tissue oxygenation and flow indicative of ischemic complications and to standardize the methods.

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Section: Polarographic Measurement Of Oxygen Tensionmentioning

confidence: 86%

How to assess intestinal viability during surgery: A review of techniques

Urbanavičius

Pattyn²,

Putte³

et al. 2011

WJGS

188

156

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“…Blood testing for haemostatic markers was undertaken on patients systemic circulation, preoperatively with anastomotic leak and 17 age-and sex-matched control patients from and postoperatively, causing an the same cohort. Samples were taken for analysis of: prothrombin fragment impaired healing process 1 and 2, enzyme-inhibitor complexes produced during activation (thrombin-antithrombin complexes) and soluble fibrin Jacobi et al, Surgery: oesophagectomy (n = 33) Definition: none 1998, 224 …”

Section: Medline and Healthstarmentioning

confidence: 99%

The measurement and monitoring of surgical adverse events

Bruce

Russell

Mollison

et al. 2001

Health Technol Assess

297

209

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. Contact Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK.We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTAThe measurement and monitoring of surgical adverse events NHS R&D HTA ProgrammeT he NHS R&D Health Technology Assessment (HTA) Programme was set up in 1993 to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS.Initially, six HTA panels (pharmaceuticals, acute sector, primary and community care, diagnostics and imaging, population screening, methodology) helped to set the research priorities for the HTA Programme. However, during the past few years there have been a number of changes in and around NHS R&D, such as the establishment of the National Institute for Clinical Excellence (NICE) and the creation of three new research programmes: Service Delivery and Organisation (SDO); New and Emerging Applications of Technology (NEAT); and the Methodology Programme.Although the National Coordinating Centre for Health Technology Assessment (NCCHTA) commissions research on behalf of the Methodology Programme, it is the Methodology Group that now considers and advises the Methodology Programme Director on the best research projects to pursue.The research reported in this monograph was funded as project number 97/16/04.The views expressed in this publication are those of the authors and not necessarily those of the Methodology Programme, HTA Programme or the Department of Health. The editors wish to emphasise that funding and publication of this research by the NHS should not be taken as implicit supp...

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“…After gastric pull up in the neck the tissue oxygen tension drops further down to almost half the values measured before gastrolysis. It is however not clear how far impaired tissue oxygenation in itself is responsible for anastomotic leak rather than cellular metabolic disorders or technical factors as indeed there seems to be no significant evidence of decreased tissue oxygen levels in patients with anastomotic complications [9]. In this respect a wide variety of surgery-related aspects including technical failures may interfere substantially with the occurrence of anastomotic complications.…”

Section: Etiologymentioning

confidence: 99%

Anastomotic Complications after Esophagectomy

Lerut¹,

Coosemans²,

Decker³

et al. 2002

Dig Surg

171

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Anastomotic complications after esophagectomy continue to be a burden jeopardizing the quality of life and of swallowing. However, incidence, mortality and morbidity of anastomotic complications have substantially decreased in recent years. It seems that this is not so much related to the use of a particular conduit, approach or route for reconstruction, but rather related to refinement in anastomotic techniques and perhaps even more to progress in modern perioperative management. Knowledge of surgical anatomy and meticulous technique are of paramount importance and obviously related to individual expertise. As to the management, most leaks can be treated by conservative measures and reintervention surgery today is rather exceptional. Early endoscopy and dilatation seem to decrease the incidence and severity of anastomotic stenosis.

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Is Tissue Oxygen Tension during Esophagectomy a Predictor of Esophagogastric Anastomotic Healing?

Cited by 35 publications

References 9 publications

How to assess intestinal viability during surgery: A review of techniques

How to assess intestinal viability during surgery: A review of techniques

The measurement and monitoring of surgical adverse events

Anastomotic Complications after Esophagectomy

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