Is this the time for Magnesium sulfate to replace Meperidine as an antishivering agent in spinal anesthesia?

Elsonbaty, Mohamed; Elsonbaty, Ahmed; Saad, Dalia

doi:10.1016/j.egja.2013.03.002

Cited by 13 publications

(30 citation statements)

References 22 publications

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“…Magnesium sulphate is found to be effective in management of postoperative shivering after general anesthesia as well as spinal anesthesia [44,45]. Elsonbaty et al found magnesium sulphate to be an effective way for the control of shivering and suggested that it could replace meperidine for treatment of shivering during spinal anesthesia with low incidence of side effects.…”

Section: Management Of Shiveringmentioning

confidence: 99%

“…Antishivering effect may be due to blocking of NMDA receptors leading to a decrease in norepinephrine and 5 HT as both of these have role in thermoregulatory control. Magnesium sulphate is an attractive choice for shivering control because hypomagnesemia is observed during induced hypothermia [45]. Ibrahim et al further observed that following spinal anesthesia prophylactic magnesium sulphate infusion lowered the incidence of shivering [46].…”

Section: Management Of Shiveringmentioning

confidence: 99%

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Magnesium: Emerging Potentials in Anesthesia Practice

Bansal¹

2015

J Anesth Clin Res

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Magnesium, a non-competitive blocker of N-methyl-D-aspartate receptor, initially used for management of preeclampsia, arrhythmia and bronchial asthma, is of great importance in anesthesia practice nowadays. It is being used intravenously, intrathecally as well as epidurally for postoperative pain relief. Recently it has gained popularity as an adjuvant in blocks. Anesthetic and analgesic sparing characteristics of magnesium enable anesthesiologists to reduce the dose of anesthetics during surgery and the use of analgesics after surgery.

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Section: Management Of Shiveringmentioning

confidence: 99%

Section: Management Of Shiveringmentioning

confidence: 99%

Magnesium: Emerging Potentials in Anesthesia Practice

Bansal¹

2015

J Anesth Clin Res

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“…35 Mahoori et al 35 found that ondansetron, 8 mg, was as effective as meperidine, 25 mg, for POS. Elsonbaty et al 37 found that the use of magnesium sulfate for controlling shivering in patients receiving spinal anesthesia was effective.…”

Section: Painmentioning

confidence: 98%

“…36 When further treatment is needed, meperidine is the most common drug used to treat POS. 37 Meperidine versus other opioids is used because it reduces the shivering threshold (the core temperature that triggers the shivering response). 38 However, because it is an opioid, its use can contribute to drowsiness, PONV, and a delayed discharge.…”

Section: Painmentioning

confidence: 99%

Timely Patient Discharge From the Ambulatory Surgical Setting

Maurice¹

2015

AORN Journal

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“…Kejadian tersebut merupakan salah satu komplikasi dari hipotermia yang terjadi perioperatif. 1 Konsumsi oksigen dan juga produksi karbon dioksida dapat meningkat sebanyak 2-3 kali lipat dan dapat terjadi asidosis laktat selama pasien menggigil. Hal tersebut akan menjadi masalah pada pasien dengan cadangan fungsi kardiopulmonal yang sangat terbatas.…”

Section: Pendahuluanunclassified

Perbandingan Efek Pencegahan Magnesium Sulfat dengan Petidin Intravena terhadap Kejadian Menggigil Selama Operasi Reseksi Prostat Transuretra dengan Anestesi Spinal

Gunadi¹,

Fuadi²,

Bisri³

2015

JAP

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Gangguan termoregulasi berupa menggigil sering terjadi selama operasi dengan anestesi spinal. Tujuan penelitian ini membandingkan efek pencegahan kejadian menggigil selama operasi reseksi prostat transuretra dalam anestesi spinal antara MgSO 4 dan petidin. Penelitian ini merupakan uji klinis acak terkontrol tersamar ganda pada 42 pasien dengan status fisik American Society of Anesthesiologist (ASA) II atau III, usia 60−70 tahun yang menjalani operasi reseksi prostat transuretra di kamar operasi bedah sentral Rumah Sakit Dr. Hasan Sadikin Bandung pada bulan Maret-September 2014. Pasien dibagi dalam kelompok MgSO 4 dan kelompok petidin. Data karakteristik, kejadian menggigil, suhu tubuh inti, monitoring tanda vital, dan efek samping dicatat. Hasil penelitian menunjukkan efek pencegahan kejadian menggigil kelompok MgSO 4 lebih baik dibanding dengan kelompok petidin dan kejadian menggigil di kamar operasi 4/21 vs 9/21, sedangkan di ruang pemulihan kejadian menggigil sama pada kedua kelompok (1/21). Simpulan penelitian ini menunjukkan pemberian MgSO 4 intravena sebelum anestesi spinal secara klinis mengurangi kejadian menggigil selama operasi dan memiliki efek pencegahan menggigil yang lebih baik dibanding dengan petidin.

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Is this the time for Magnesium sulfate to replace Meperidine as an antishivering agent in spinal anesthesia?

Cited by 13 publications

References 22 publications

Magnesium: Emerging Potentials in Anesthesia Practice

Magnesium: Emerging Potentials in Anesthesia Practice

Timely Patient Discharge From the Ambulatory Surgical Setting

Perbandingan Efek Pencegahan Magnesium Sulfat dengan Petidin Intravena terhadap Kejadian Menggigil Selama Operasi Reseksi Prostat Transuretra dengan Anestesi Spinal

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