Is there unique difference in the type of renal stones in Northern Sri Lanka?  Analysis of chemical composition of renal stones in Jaffna by infrared spectroscopy

Rajendra, S.

doi:10.4038/sljs.v38i1.8688

Cited by 4 publications

(7 citation statements)

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“…The complicated urinary tract in males causes over-acidification of urine, causing increased excretion of oxalates and uric acid and suppressing the excretion of citrate, an inhibitor of stone formation. 10 The highest frequency of stones in our study is in the age group 21 to 40 years, followed by 41 to 60 years. Joshi et al also reported the highest renal stone prevalence in the same age group in their study in Nepal, 12 as reported by Samad et al 13 Calcium oxalate stones were found to be most abundant in our results, i.e.…”

Section: Discussionmentioning

confidence: 46%

“…9 Infrared spectroscopy is considered a primary technique to analyse the composition of renal stones. 10 The purpose of this study was to differentiate stones qualitatively. Analysis of stone composition is essential for treating underlying causes and preventing stone recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…9 Furthermore, this technique is preferred due to fast detection and less specimen requirement. 10 Therefore our study aimed to determine the frequency of renal stones of various chemical compositions in our setup to treat and prevent their recurrence.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of Frequency and Composition of Renal Stones in a Reference Laboratory of Pakistan

Bibi

Aamir

Riaz

et al. 2023

PAFMJ

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Objective: To determine frequency and chemical composition of renal stones in Northern Pakistan using FTIR Spectroscopy. Study Design: Cross-sectional study Place and Duration of Study: Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi Pakistan, from Jan 2017 to Jul 2020. Methodology: One thousand and twenty-nine stones were analysed in 3 years at AFIP of patients aged from 1 to 98 years. They were analysed by Automatic FT-IR type IRAffinity-1. The results were verified by manual analysis of spectrograms and then confirmed by standard peaks feed on NICODOM LIBRARY. Results: Calcium oxalate stones were the most frequent (1065,80.1%), followed by uric acid stones (179,13.5%), mixed stones (44,3.3%), calcium appetite (31,2.3%), struvite (6,0.5%), hydroxy appetite (1,0.1%) and cysteine stones (3,0.2%). Male predominance was noted in patients with renal stones (1057,79.5%). The majority of the patients were from the age group 21 –40 years (47.5%) Conclusion: Calcium oxalate stones are most commonly followed by uric acid stones in patients of northern Pakistan. The frequency of renal stones is high in male patients.

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Section: Discussionmentioning

confidence: 46%

Section: Discussionmentioning

confidence: 99%

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Assessment of Frequency and Composition of Renal Stones in a Reference Laboratory of Pakistan

Bibi

Aamir

Riaz

et al. 2023

PAFMJ

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“…When looking at the Sri Lankan data, a study among 50 patients from different climatic zones found that the male-to-female ratio was 2.6: 1 [8]. A study done in Northern Sri Lanka found that 74% of patients seeking surgical treatment for renal stones were males [9]. The majority of the patients belonged to the age group 40-59.…”

Section: Discussionmentioning

confidence: 99%

The Spectrum the Disease and Metabolic Evaluation in Urolithiasis Patients: A Prospective Study in a Tertiary Urology Centre.

Balagobi,

Thangarajah,

Thuraisamy Sarma

et al. 2024

Preprint

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Introduction Urolithiasis, a prevalent urological condition (8-13% globally) exhibits regional variations, influenced by water quality, climate, health factors and diet. Sri Lanka with its tropical climate and dietary patterns is part of the "Stone Belt" of Asia. This study in Northern Sri Lanka examines urinary stone compositions and assesses the prevalence of metabolic disorders among urolithiasis patients. Methods This prospective cross-sectional study, conducted at tertiary urology centre from July 2022 to June 2023, focused on surgically treated urolithiasis patients. Institutional ethical clearance was obtained. Patient details and investigational findings were collected through questionnaires and data extraction forms. Stone analysis utilized Fourier transform infrared spectroscopy and detailed metabolic evaluation of 24 hour urine collection sample is carried out. Results This study followed 153 surgically treated urolithiasis patients, primarily male (64.3%), mean age 48.64. Ureteric colic (48.4%) was common, with kidney stones (45.8%) prevalent; 57.52% had recurrent stones. Diabetes mellitus (DM=23.5%) was the top comorbidity. Calcium oxalate monohydrate (COM) stones (78.4%) were most frequent, followed by uric acid (12.4%). COM predominated in 40-59 age group. No significant gender-stone type association. 86.9% had metabolic abnormalities, notably hypocitraturia (60.1%). 23% had both hypocitraturia and hypomagnesuria. Some metabolic disorders showed gender differences, with a marginal age-metabolic disorders association (p < 0.061). Urine oxalate levels were normal with higher variability in males. Conclusion Middle-aged males with urolithiasis commonly presented with ureteric colic and predominantly had calcium oxalate monohydrate stones. Recurrent stones were common, often accompanied by metabolic abnormalities such as hypocitraturia and hypomagnesuria, with diabetes mellitus as the primary comorbidity.

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“…The European Association of Urology (EAU) guidelines recommend renal stone chemical composition analysis as an important investigation to initiate steps for prevention of recurrent stones [1,2]. While calcium oxalate is the commonest type of renal stone in Jaffna, incidence of uric acid stone has increased over the past three decades and this has been related to the metabolic syndrome [3].…”

Section: Introductionmentioning

confidence: 99%

Metabolic evaluation of patients with recurrent, multiple or bilateral renal stones in Jaffna

Rajendra

2020

Ceylon Med. J.

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Is there unique difference in the type of renal stones in Northern Sri Lanka? Analysis of chemical composition of renal stones in Jaffna by infrared spectroscopy

Cited by 4 publications

References 0 publications

Assessment of Frequency and Composition of Renal Stones in a Reference Laboratory of Pakistan

Assessment of Frequency and Composition of Renal Stones in a Reference Laboratory of Pakistan

The Spectrum the Disease and Metabolic Evaluation in Urolithiasis Patients: A Prospective Study in a Tertiary Urology Centre.

Metabolic evaluation of patients with recurrent, multiple or bilateral renal stones in Jaffna

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