Is there any progress in the search for the ideal conduit for reconstruction of the right ventricular outflow tract in young children?

Cleuziou, Julie

doi:10.21037/tp.2018.06.02

Cited by 6 publications

(2 citation statements)

References 12 publications

(11 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To date, the ideal material for use in pediatric cardiac surgery has not been identified [58] as only optimized but no optimal materials are available.…”

Section: Conclusion and Future Challengesmentioning

confidence: 99%

Grafts and Patches: Optimized but Not Optimal Materials for Congenital Heart Surgery

et al. 2023

View full text Add to dashboard Cite

A variety of materials are available for the surgery of children with congenital heart defects. In addition to growth-related mismatch, degeneration of the material in particular frequently leads to reoperation. Therefore, the choice of conduits and patches should be made carefully. This article provides an overview of the most commonly implanted materials in pediatric cardiac surgery.Structural changes can be detected in all available materials. Depending on the age at implantation and the site of implantation, the extent and time course of material degeneration vary. Autologous material is still the gold standard in reconstructive surgery. Biological materials have largely replaced artificial materials in clinical use.The search for the ideal material continues. In pediatric cardiac surgery, there are only optimized but no optimal materials.

show abstract

“…To date, the ideal material for use in pediatric cardiac surgery has not been identified [58] as only optimized but no optimal materials are available.…”

Section: Conclusion and Future Challengesmentioning

confidence: 99%

Grafts and Patches: Optimized but Not Optimal Materials for Congenital Heart Surgery

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Ditkowski et al and Leeten et al used bioreactors to model BJVC behaviours - bacterial adherence and endothelialization, respectively ( Ditkowski et al, 2019 ; Leeten et al, 2021 ), whereas many other researchers attempted to achieve cell repopulation of decellularized conduits with bioreactors ( Teebken et al, 2003 ; Lichtenberg et al, 2006 ; Yuan et al, 2016 ; Iacobazzi et al, 2021 ; Rapetto et al, 2022 ). Although the development of an ideal bioreactor and a standard conduit-engineering protocol is still in it is infancy, a decellularized BJVC repopulated with autologous cells offering a close-to-autograft operation choice may well be where the future lies ( Cleuziou, 2018 ).…”

Section: Future Prospectsmentioning

confidence: 99%

Current development of bovine jugular vein conduit for right ventricular outflow tract reconstruction

Xie

Tan³

et al. 2022

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Right ventricular outflow tract (RVOT) reconstruction is a common surgical method to treat congenital cardiac lesions, and bovine jugular vein conduit (BJVC) has become a prevalent candidate of prosthetic material for this procedure since 1999. Although many clinical studies have shown encouraging results on BJVCs, complications such as stenosis, aneurysmal dilatation, valve insufficiency, and infective endocarditis revealed in other clinical outcomes still remain problematic. This review describes the underlying mechanisms causing respective complications, and summarizes the current technological development that may address those causative factors. Novel crosslinking agents, decellularization techniques, conduit coatings, and physical reinforcement materials have improved the performances of BJVCs. The authors expect that the breakthroughs in the clinical application of BJVC may come from new genetic research findings and advanced characterization apparatuses and bioreactors, and are optimistic that the BJVC will in the future provide sophisticated therapies for next-generation RVOT reconstruction.

show abstract

Right Ventricle to Pulmonary Artery Conduit With Tricuspid Expanded Polytetrafluoroethylene Valves

Kobayashi

Shinkawa

Yamagishi

et al. 2021

The Annals of Thoracic Surgery

View full text Add to dashboard Cite

Is there any progress in the search for the ideal conduit for reconstruction of the right ventricular outflow tract in young children?

Cited by 6 publications

References 12 publications

Grafts and Patches: Optimized but Not Optimal Materials for Congenital Heart Surgery

Grafts and Patches: Optimized but Not Optimal Materials for Congenital Heart Surgery

Current development of bovine jugular vein conduit for right ventricular outflow tract reconstruction

Right Ventricle to Pulmonary Artery Conduit With Tricuspid Expanded Polytetrafluoroethylene Valves

Contact Info

Product

Resources

About