Is there a correlation between preoperative neutrophil-to-lymphocyte, platelet-to-lymphocyte, and lymphocyte-to-monocyte ratios and postoperative pain in video-assisted thoracoscopic surgery?

Ulger, Gulay; Baldemir, Ramazan; Zengin, Musa; Sazak, Hilal; Alagöz, Ali

doi:10.1097/md.0000000000029472

Cited by 3 publications

(4 citation statements)

References 39 publications

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“…A high N/L ratio in the preoperative period has been noted to be associated with high postoperative pain scores and analgesic consumption. [24][25][26] The preoperative Neutrophil, Lymphocyte, and N/L ratios of the patients included in our study were similar among the groups. Therefore, it can be stated that these markers did not affect the postoperative pain status as the groups were similar in terms of inflammatory parameters in the preoperative period.…”

Section: Discussionmentioning

confidence: 92%

Analgesic effects of thoracic fascial plane blocks in postoperative pain management following cardiac surgery with sternotomy: a retrospective study

Zengin,

Salman

2024

Anatolian Curr Med J / ACMJ / acmj

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Aims: Acute poststernotomy pain is very severe and causes adverse hemodynamic disturbances. Various thoracic fascial plane blocks are used in the management of this pain. This study aimed to compare the analgesic effects of conventional analgesic methods and thoracic fascial plane blocks in the treatment of post-sternotomy pain. Methods: Patients aged over than 18 years and with American Society of Anesthesiologists (ASA) physical status I-II-III who underwent elective cardiac surgery with sternotomy in 2022-2023 were included in this retrospective study. Patient records were categorized into groups based on the regional analgesia preferences applied. The groups are as follows: Group I: Patients without any blocks. Group II: Patients who received parasternal block (PSB). Group III: Patients who received serratus anterior plane block (SAPB). Group IV: Patients who received erector spinae plane block (ESPB). Then, the patients’ demographic data, laboratory data, Behavioral Pain Score (BPS) values, Visual Analog Scale (VAS) values, and additional analgesia needs were recorded and compared. Results: The files of 128 patients were included in the study. The patients are statistically similar in terms of demographic data and surgical characteristics. Remifentanil consumption, BPS values, VAS values, and the need for additional analgesia were statistically lower in the groups in which thoracic fascial plane blocks were applied compared to the group in which conventional analgesia was applied. Conclusion: As a result, thoracic fascial plane blocks, which have been used increasingly frequently in recent years, can provide more effective analgesia than conventional analgesia methods in cardiac surgery. Additionally, considering enhanced recovery after surgery protocols, these blocks may reduce undesirable side effects by limiting the need for opioids in the perioperative period. Since PSB and SAPB can be applied in the supine position, they may be more advantageous than ESPB in terms of ease of application.

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Section: Discussionmentioning

confidence: 92%

Analgesic effects of thoracic fascial plane blocks in postoperative pain management following cardiac surgery with sternotomy: a retrospective study

Zengin,

Salman

2024

Anatolian Curr Med J / ACMJ / acmj

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“…Pain after VATS is a common condition and adequate control of postoperative pain in patients undergoing VATS is very important for the prevention of pulmonary complications (17). Adequate management of postoperative pain provides early mobilization, lowers hospital stay, lowers costs, and increases patient satisfaction (18)(19)(20)(21).…”

Section: Discussionmentioning

confidence: 99%

“…For the early mobilization of patients after surgery, coughing should be ensured so that lung secretions can be cleared. This can only be possible by providing adequate analgesia to the patient (17,22). However, with using more opioids than necessary while providing postoperative pain control, side effects, such as respiratory depression and…”

Section: Discussionmentioning

confidence: 99%

The effects of body mass index on postoperative pain in patients undergoing thoracic paravertebral block after video-assisted thoracoscopic surgery: A retrospective analysis

Ulger

Zengin

Baldemir

2022

Journal of Health Sciences and Medicine

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Aim: Postoperative pain is an important problem in patients undergoing video-assisted thoracic surgery (VATS). Thoracic paravertebral block (TPVB) is among the commonly used techniques for pain control after VATS. Despite the analgesic methods applied, the desired level of pain control can not be achieved in all patients. Therefore, clinicians and researchers are interested in factors affecting postoperative pain. One factor is the relationship between postoperative pain and body mass index (BMI). Although it has been reported that acute or chronic pain is more common in the general population with a BMI, the relationship between postoperative pain and BMI is still controversial. This study aims to investigate the effects of BMI on postoperative pain in patients who underwent TPVB in the treatment of pain after VATS. Material and Method: Patients who had elective VATS and TPVB were included in the study. Patients who underwent TPVB with ultrasonography (USG) and postoperative intravenous (iv) morphine patient-control-analgesia (PCA) for postoperative analgesia were divided into three groups according to BMI. Group-I BMI: 18-24.99 kg/m2, Group-II BMI: 25-29.9 kg/m2, Group-III BMI: 30-40 kg/m2. Results: 146 patients were included in the study. There was no significant difference between the postoperative 30th minute, 1st hour, 6th hour, 12th hour, and 24th-hour VAS values of the patients in Group-I, Group-II, and Group-III. There was no statistically significant difference in terms of morphine consumption, additional analgesic requirement, and complications in all three groups. Conclusion: It was determined that there was no relationship between BMI and postoperative pain scores in the first 24 hours in patients who underwent TPVB after VATS. In addition, it was determined that postoperative morphine consumption and additional analgesic needs were not associated with BMI. Effective pain control can be achieved in all patients, regardless of BMI, with effective peripheral nerve blocks and analgesics using practical imaging techniques such as USG.

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“…As mentioned in the previous reports, preoperative inflammatory biomarkers had been independent predictors of prognostic markers who undergo thoracic surgery, potentially linked to smoking. [38][39][40] In addition, there were found that preoperative inflammatory parameters were associated with postoperative pain in many operations, [41][42][43][44][45] but the relationship between them was still controversial. In this study, we found the relevance between neutrophils and CPSP in elderly patients.…”

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confidence: 99%

Development and Validation of a Prediction Model for Chronic Post-Surgical Pain After Thoracic Surgery in Elderly Patients: A Retrospective Cohort Study

Wu¹,

Zeng²,

Yu³

et al. 2022

JPR

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Purpose Chronic post-surgical pain (CPSP) is one of the adverse outcomes after surgery, especially in thoracotomy. However, the prevalence of CPSP in elderly adults (≥65 years), is still limited. Therefore, the present study was undertaken to establish and validate the prediction model of CPSP in those patients after thoracic surgery, including thoracotomy and video-assisted thoracoscopic surgery. Patients and Methods This retrospective, observational single-center cohort study was conducted in Nanfang Hospital, Southern Medical University, which randomly and consecutively collected 577 elderly patients who underwent thoracic surgery between January 1, 2017, and December 31, 2020. According to the Akaike information criterion, the prediction model was built based on all the data and was validated by calibration with 500 bootstrap samples. Results The mean age of participants was 69.09±3.80 years old, and 63.1% were male. The prevalence of CPSP was 26.9%. Age more than 75 years, BMI, blood loss, longer length of hospital stays, and higher pre-operative neutrophil count were associated with CPSP. Except for these factors, we incorporated history of drinking to build up the prediction model. The areas under the curve (AUCs) of the prediction models were 0.66 (95% CI, 0.61–0.71) and 0.64 (95% CI, 0.59–0.69) in the observational and validation cohorts, respectively. And the calibration curve of the predictive model showed a good fit between the predicted risk of CPSP and observed outcomes in elderly patients. Conclusion The present developed model may help clinicians to find high-risk elderly patients with CPSP after thoracic surgery and take corresponding measures in advance to reduce the incidence of CPSP and improve their life quality.

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Is there a correlation between preoperative neutrophil-to-lymphocyte, platelet-to-lymphocyte, and lymphocyte-to-monocyte ratios and postoperative pain in video-assisted thoracoscopic surgery?

Cited by 3 publications

References 39 publications

Analgesic effects of thoracic fascial plane blocks in postoperative pain management following cardiac surgery with sternotomy: a retrospective study

Analgesic effects of thoracic fascial plane blocks in postoperative pain management following cardiac surgery with sternotomy: a retrospective study

The effects of body mass index on postoperative pain in patients undergoing thoracic paravertebral block after video-assisted thoracoscopic surgery: A retrospective analysis

Development and Validation of a Prediction Model for Chronic Post-Surgical Pain After Thoracic Surgery in Elderly Patients: A Retrospective Cohort Study

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