Is the Western diet adequate in copper?

Klevay, Leslie M.

doi:10.1016/j.jtemb.2011.08.146

Cited by 92 publications

(62 citation statements)

References 148 publications

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“…As described above, surgical obesity treatment has also been strongly implicated in copper deficiency, likely by causing a diminished absorption of copper after a gastric bypass surgery (16)(17)(18). In addition, low copper levels were detected in organs, plasma and tissue of patients with several chronic diseases including cardiovascular disease, central nervous system, and musculoskeletal disorders (25). In fact, it was suggested that an ischemic heart disease could be largely attributed to copper deficiency (26), and that Cu deficiency and the high sugar consumption characteristic in the Western diet may interact in CVD (27).…”

Section: Low Copper and Human Diseasementioning

confidence: 98%

The Role of Copper as a Modifier of Lipid Metabolism

Burkhead¹,

Lutsenko²

2013

Lipid Metabolism

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Section: Low Copper and Human Diseasementioning

confidence: 98%

The Role of Copper as a Modifier of Lipid Metabolism

Burkhead¹,

Lutsenko²

2013

Lipid Metabolism

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“…A high ratio of Zn/Cu increases the risk for hypercholesterolemia in animals and humans, and such observation has been made with regard to use of Zn supplementation and conventional diet including low Cu foods [11].…”

Section: Introductionmentioning

confidence: 99%

Serum copper, zinc and high-sensitivity C-reactive protein in short and long sleep duration in ageing men

Luojus

Lehto

Tolmunen

et al. 2015

Journal of Trace Elements in Medicine and Biology

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“…Cu deficiency is known to affect the cardiovascular, musculoskeletal and nervous systems, to impair the metabolism of cholesterol and glucose and to affect the function of the hepatic antioxidative system 19. Aigner et al 20.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for development of nonalcoholic fatty liver disease after pancreatoduodenectomy

Fujii

Nanashima

Hiyoshi

et al. 2017

Annals of Gastroent Surgery

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Considerable attention has been focused on nonalcoholic fatty liver disease (NAFLD) which occasionally develops after pancreatoduodenectomy (PD). The present study aimed to clarify the prevalence, sequential change in properties and risk factors for NAFLD development after PD. We enrolled 196 patients who underwent PD and a computed tomography (CT) scan 1 month, 6 months and 1 year after surgery. NAFLD was defined as a liver‐to‐spleen attenuation ratio on plain CT of <0.9. We compared various clinical factors between the NAFLD group and the control group. Individual prevalence of NAFLD at 1 month, 6 months and 1 year after surgery was 12%, 21% and 15%. Significantly different factors by univariate analysis were as follows: 1 month: age, sex, total protein (TP), total cholesterol (TC) and copper (Cu); 6 months: sex, disease, surgical method, portal vein resection (PVR), frequency of defecation, TC and Cu; 1 year: age, sex, disease, surgical method, PVR, frequency of defecation, TP and Cu. Risk factors by multivariate analysis were as follows: 1 month: not elderly age, female sex and a decrease in Cu; 6 months: female sex and a decrease in Cu; 1 year: a decrease in Cu. NAFLD after PD frequently developed in women with a decrease in serum Cu and was influenced by various factors related to poor digestion and absorption associated with pancreatic exocrine insufficiency.

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Is the Western diet adequate in copper?

Cited by 92 publications

References 148 publications

The Role of Copper as a Modifier of Lipid Metabolism

The Role of Copper as a Modifier of Lipid Metabolism

Serum copper, zinc and high-sensitivity C-reactive protein in short and long sleep duration in ageing men

Risk factors for development of nonalcoholic fatty liver disease after pancreatoduodenectomy

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