Is the BCG test of diagnostic value in tuberculosis?

Göçrnen, A.; Ki̇per, Nural; Ertan, Ülker; Kalaycı, Ömer; Özçeli̇k, Uğur

doi:10.1016/0962-8479(94)90103-1

Cited by 14 publications

(10 citation statements)

References 7 publications

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“…15 A Turkish study done by Gocmen et al 16 showed even more positivity of BCG test as compared to the mantoux test in childhood pulmonary tuberculosis. In that study they found that BCG test was positive in 100% of patients as compared to 44.5% mantoux positive in clinically suspected cases of TB.…”

Section: Discussionmentioning

confidence: 99%

Frequency of Positive Results of Bacille Calmette Gurein and Mantoux Skin Tests in Suspected Cases of Childhood Pulmonary Tuberculosis

Usman¹,

Aleem²,

Hassan³

2016

Annals KEMU

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Objective: To determine the frequency of positive results of Bacille Calmette Gurein and Mantoux skin tests in suspected cases of childhood pulmonary tuberculosis. Patients and Methods:This prospective interventional study was conducted on 160 children from outpatient and inpatient departments of Pediatrics in Services institute of medical sciences, Lahore. An informed consent was taken from their parents for using their data in research and to keep the results confidential. Cases were diagnosed on the basis of history, examination and investigations. Each patient was given 0.1 ml BCG intradermally on left shoulder and 5 IU of PPD intradermally on volar aspect of right forearm. The results were observed after 48 hours of application in the form of induration (in mm). as positive. All the information was recorded in a predesigned proforma. Results: Out of 160 patients, 83 (51.9%) were males and 77 (48.1%) were females. It was found that 72 (45%) patients showed positive response to both mantoux test and BCG. While alone BCG test was positive in 56 (35%) patients. Both BCG and mantoux tests were negative in rest of 32 (20%) patients. 131(81.9%) patients had variable degree of malnutrition. Severe malnutrition was present in 54 patients; out of these, 50 (92.6%) patients were BCG positive while only 10 (18.5%) patients showed positive response to mantoux test. Conclusion: BCG is more reliable than the tuberculin test in the diagnosis of childhood pulmonary tuberculosis.

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Section: Discussionmentioning

confidence: 99%

Frequency of Positive Results of Bacille Calmette Gurein and Mantoux Skin Tests in Suspected Cases of Childhood Pulmonary Tuberculosis

Usman¹,

Aleem²,

Hassan³

2016

Annals KEMU

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“…In areas of the world where tuberculosis is common, BCG has been advocated as a diagnostic test, especially in children where vaccination is especially valuable and in whom tuberculosis is difficult to diagnose (Göçmen et al 1994). In areas of the world where tuberculosis is common, BCG has been advocated as a diagnostic test, especially in children where vaccination is especially valuable and in whom tuberculosis is difficult to diagnose (Göçmen et al 1994).…”

Section: The Bacille Calmette-guérin Testmentioning

confidence: 99%

Immunodiagnosis of Mycobacterial Infection

et al. 1999

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“…Subsequent studies in children up to 12 years of age confirmed the greater sensitivity of the BCG test (81-92% sensitivity, 82.5-100% specificity), compared with tuberculin (sensitivities 45.5-52.3%, with specificities comparable to the BCG test) 8 9 10. The BCG test was especially helpful in children who were malnourished or who had tuberculous meningitis or miliary disease.…”

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confidence: 90%

“…Complications in using the BCG vaccine without prior tuberculin skin testing were largely due to subcutaneous administration and were no more common in children with tuberculosis than in healthy children; seven of 1129 vaccinated developed regional lymphadenitis 8 9 10. A review of published and unpublished data, including a survey sponsored by the International Union against Tuberculosis, recorded 10 371 complications following almost 1.5 billion BCG vaccinations in adults and children 11.…”

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confidence: 99%