Is surgical resection indicated for a solitary non–small cell lung cancer recurrence?

Abstract

Resection of a solitary non-small cell lung cancer recurrence might provide long-term survival in highly selected patients. However, surgical resection might be contraindicated if the primary tumor is stage II or III.

Solitary metachronous gastric metastasis from pulmonary adenocarcinoma: Report of a case

“…However some investigators showed long-term survival after operative treatments in selected patients; Hishida et al reported a satisfactory outcome after resection of lung cancer recurrence in stage I patients. 18 Aokage et al observed prolonged survival after surgery in two patients with diagnosis of solitary gastric metastasis from pulmonary pleomorphic carcinoma. 19 Moreover surgical treatment of such recurrences may be indicated if bleeding or obstruction is encountered.…”

Integrated imaging of non-small cell lung cancer recurrence: CT and PET-CT findings, possible pitfalls and risk of recurrence criteria

“…When possible, surgical resection is reported to be the best approach [18]. Other authors would only consider reintervention when the primary tumour was determined to be stage I disease [74].…”

Therapeutic strategy for postoperative recurrence in patients with non-small cell lung cancer

“…Such limited metastases are referred to as oligometastases. Local therapy, such as surgery and radiotherapy, has been applied successfully in appropriately selected patients, especially for patients with either brain metastasis alone or those with adrenal metastasis alone [31][32][33][34] . Recently, Yano et al reported a retrospective study reviewing their therapeutic experience with postoperatively recurrent NSCLC patients and demonstrated that a histology of adenocarcinoma, a longer disease-free interval (≥ 1 year) and the use of local therapy are significantly preferable prognostic factors for the postrecurrence OS of patients with distant metastasis alone [6] .…”