Is stress cardiomyopathy the underlying cause of ventricular dysfunction associated with brain death?

Berman, Marius; Ali, Ayyaz; Ashley, Euan A.; Freed, Darren H.; Clarke, Kieran; Tsui, Steven; Parameshwar, Jayan; Large, Stephen

doi:10.1016/j.healun.2010.04.008

Cited by 69 publications

(55 citation statements)

References 39 publications

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“…Very recently, a temporary myocardial dysfunction, characterized by a clinical picture similar to that of TTC and probably sharing a catecholamine-mediated pathophysiology, has been described after subarachnoid hemorrhage [45] and in donor hearts after cardiac transplantation as well [46]. Interestingly, also for subarachnoid hemorrhage (and hemorrhagic stroke as well), a circadian morning pattern has already been described by our group [47,48].…”

Section: Discussionmentioning

confidence: 64%

Tako-tsubo cardiomyopathy: is there a preferred time of onset?

et al. 2010

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The occurrence of major cardiovascular events is not randomly distributed over time, but exhibits chronobiological patterns, i.e., circadian, weekly, or seasonal. No systematic studies on the temporal preference of onset of Tako-tsubo cardiomyopathy (TTC) are known. We performed a computer-assisted search of the literature (from 2000 to January 2010), with the following search terms: transient left ventricular apical ballooning syndrome, takotsubo-like left ventricular dysfunction, ampulla cardiomyopathy, tako-tsubo or takotsubo cardiomyopathy, tako-tsubo, apical ballooning. Criteria for publication inclusion were (a) reporting of original data, (b) inclusion of at least 30 or more cases, (c) adherence to the requested diagnostic criteria for TTC. We focused on studies including in their purposes the "time of onset" of events. Out of the 19 studies found, 7 (4 from Europe, 1 each from Asia, Australia and USA) specifically addressed this aspect. A circadian (morning) and a seasonal (summer) higher frequency of events was found. TTC seems to exhibit a temporal variation of onset, with preferred peaks during morning and summer. Stress and catecholamines, also according to their temporal organization, might play a pivotal role. The demonstration of time frames characterized by highest frequency of occurrence might help to try to ensure maximal protection during particularly vulnerable periods.

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Section: Discussionmentioning

confidence: 64%

Tako-tsubo cardiomyopathy: is there a preferred time of onset?

et al. 2010

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“…Th ese and other studies suggest that TC may very well be part of the spectrum of so-called neurogenic stress cardiomyopathy, an increasingly acknowledged phenomenon accompanying nearly 50% patients with brain death (8). Th e salient feature of this clinical entity is its reversibility, i.e., the spontaneous normalization of cardiac function.…”

Section: Invited Commentarymentioning

confidence: 97%

Successful Heart Transplantation Using a Donor Heart Afflicted by Takotsubo Cardiomyopathy

Ravi

Campagna

Rosas

et al. 2016

Baylor University Medical Center Proceedings

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“…Unfortunately only 1 in 8 hearts offered for donation is accepted for transplantation (1). Some donor hearts may be rejected due to left ventricular systolic dysfunction (LVSD) noted on initial assessment (2).…”

Section: Implications Regarding Use Of Dysfunctional Hearts For Succementioning

confidence: 99%