Successful Heart Transplantation Using a Donor Heart Afflicted by Takotsubo Cardiomyopathy

Ravi, Y.; Campagna, Ryan J.; Rosas, Paola C; Essa, Essa Ibrahim; Hasan, Ayesha; Higgins, Robert S.D.; Emani, Sitaramesh; Sai-Sudhakar, Chittoor

doi:10.1080/08998280.2016.11929367

Cited by 7 publications

(2 citation statements)

References 5 publications

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“…These hearts may even be successfully transplanted before fully recovered, with subsequent recovery in the recipient. 204,205 This may also apply to potential donors with a heart exhibiting TTCM following cardiac resuscitation in which epinephrine was employed. 206 Takotsubo cardiomyopathy and pheochromocytoma…”

Section: Takotsubo Cardiomyopathy Associated With Electroconvulsive Tmentioning

confidence: 99%

Takotsubo cardiomyopathy and its relevance to anesthesiology: a narrative review

Hessel

2016

Can J Anesth/J Can Anesth

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Section: Takotsubo Cardiomyopathy Associated With Electroconvulsive Tmentioning

confidence: 99%

Takotsubo cardiomyopathy and its relevance to anesthesiology: a narrative review

Hessel

2016

Can J Anesth/J Can Anesth

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“…If needed, coronary angiography might be considered. 20) Coordination with hospital organ procurement organizations is required to minimize non-utilization of donor hearts which are potentially acceptable. 3) 17) …”

Section: Discussionmentioning

confidence: 99%

Donor Heart Utilization in Korea

et al. 2020

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Background and Objectives Donor heart utilization patterns in Korea are not well known. We aimed to analyze the current utilization rate of donor heart and to evaluate the reason for non-utilization in Korea. Methods Brain death donors were identified from the Korean Network for Organ Sharing registry from November 2009 to December 2019. Baseline characteristics and heart transplant related parameters were compared between transplanted and discarded donor hearts. Results Among 4,401 donors, 1,383 (31.4%) hearts were utilized. Hearts from younger, male donors without history of hypertension or diabetes mellitus were utilized more frequently. The most common blood type in the transplanted group was O, while blood type A was the most common blood type in the discarded group. The ejection fraction in the discarded group were significantly lower (57.0 ± 13.5% vs. 61.7 ± 7.0%, p<0.001). Reasons for non-utilization were as follows: medical condition (34.4%), old age (31.8%), refused by all candidates (22.5%), refused to donate (11.0%), and others (0.2%). The most common cause of brain death was cerebrovascular disease in both the transplanted and discarded groups, but the incidence was significantly higher in the discarded group (46.8% vs. 37.5%, p<0.001). In multivariate analysis, old age, small body surface area, rapid heart rate, blood type other than O, abnormal echocardiography findings were independent predictors for non-utilization. Conclusions Average donor heart utilization rate was 31.4% and it improved to 42.9% in 2019. However, substantial numbers of donor hearts are still discarded. A strategic approach to improve donor heart utilization is necessary.

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