“…Rapid eye movement sleep behavior disorder (RBD) is characterized by incomplete or absent muscle paralysis during REM sleep, thus leading to forceful movements, vocalization, and dream enactment (Huang et al, 2018;Zhang et al, 2022). It is a rare diagnosis, with prevalence around 0.5%, with risk factors including prior pesticide exposure or head injury, 10.3389/fnins.2022.951147 lower educational level, male gender, increased age and prior psychiatric diagnosis (Gabryelska et al, 2018;Jung and Oh, 2021;Zhang et al, 2022). RBD can be secondary to medications or isolated RBD, and the latter is thought to be a precursor of alpha-synucleinopathies, such as Parksinson's disease, pure autonomic failure, dementia with Lewy bodies (DLB), and multiple system atrophy.…”