“…Other risk factors are contradictive in the literature, such as high nuclear grade, close (<3-2 mm) or positive margins, multifocal disease and/or large tumor size [9,13,15,21,22,24,28], yet none of these were shown to be statistically significant in our study. A history of previous contralateral breast cancer seemed to predispose to recurrence, however, given the very low number of patients in this category, we hesitate to present this as a well-proven risk factor.…”