Is positron emission tomography useful in locoregional staging of esophageal cancer? Results of a multidisciplinary initiative comparing CT, positron emission tomography, and EUS

Sandha, Gurpal; Severin, Diane; Postema, Ernst J.; McEwan, Alexander; Stewart, Ken G.

doi:10.1016/j.gie.2007.09.006

Cited by 39 publications

(18 citation statements)

References 11 publications

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“…The accuracy of EUS for N staging is 75 % [35]. EUS is superior to CT and PET for N staging; in one study, the accuracy was 81 % compared to 69 and 56 %, respectively [40]. Because the visual characteristics are subjective, diagnostic error is possible with EUS imaging alone.…”

Section: Endoscopic Ultrasoundmentioning

confidence: 99%

Esophageal Cancer

Khanna¹,

Lightdale²

2015

ERCP and EUS

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Section: Endoscopic Ultrasoundmentioning

confidence: 99%

Esophageal Cancer

Khanna¹,

Lightdale²

2015

ERCP and EUS

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“…34) Interpretation of FDG-PET /CT results is optimized by an understanding of the diagnostic limitations and pitfalls that may be encountered together with knowledge of the natural history of esophageal cancer and the staging and treatment options available. 35) A recent systemic review concluded that PET was recommended to improve the accuracy of M staging for the staging work-up of patients who were potential candidates for Invasion into a neighboring organ can be diagnosed with enhanced CT scan. Esophageal cancer (arrow) in the patient was suspected to have invaded the aorta and the left main bronchus (A).…”

Section: Evaluation Of Primary Therapy and Restagingmentioning

confidence: 99%

The New Era of Staging as a Key for an Appropriate Treatment for Esophageal Cancer

Tangoku

Yamamoto

Furukita

et al. 2012

ATCS

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Fluorodeoxyglucose-positron emission tomography (FDG-PET) and computed tomography (CT) have become the gold standard for staging of esophageal cancer by detecting distant metastases, but metastatic lymph nodes are often difficult to diagnose from the size and standardized uptake value (SUV). If we compare the diagnostic performance of endoscopic ultrasonography (EUS), CT, and FDG-PET in staging of esophageal cancer, EUS is the most sensitive method to identify the detection of regional lymph node metastases, whereas CT and FDG-PET are more specific tests. Combination study with CT, EUS and PETCT cannot make a precise diagnosis after neoadjuvant therapy (NAT). A precise staging might be determined by the fine needle aspiration biopsy (FNAB) under EUS and US screening in the neck and the abdomen even after NAT. Indication of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) for superficial cancer is sensitive because of difficulty in T1b cancer diagnosis. Detailed examination about vessel invasion and the possibility of residual tumor with dissected specimen will offer an appropriate additional therapy. New strategy like sentinel lymph node (SLN) navigation could supply more information about lymphatic routes and metastatic nodes. SLN navigation with ESD might become a new less invasive strategy for superficial esophageal cancer.

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“…In the evaluation of T parameter, EUS has a diagnostic accuracy rate of 52%-92%, but this technique is operator-dependent, with a restricted field of view and it cannot evaluate haematic and lymph node metastases. In addition, often the instrument cannot go beyond lumen strictures caused by tumor growth [13,14,15]. MRI presents the same diagnostic capability as CT, although some experiences have reported sensibility and specificity values of 100% and 84% respectively for MRI and 100% and 80% respectively for CT in the evaluation of the mediastinal invasion [12,16].…”

Section: Diagnostic Imaging Of Esophageal Carcinomamentioning

confidence: 99%

“…PET and PET-CT has demonstrated diagnostic accuracy values of 48-90% in the staging of esophageal cancer. However, these techniques are mostly used in case of advanced forms, especially for evaluating the response to combined chemo-and radiotherapic treatments [14,17,18].…”

Section: Diagnostic Imaging Of Esophageal Carcinomamentioning

confidence: 99%

“…Despite the advantages of the different techniques, MDCT currently remains the most commonly used examination in preoperative esophageal cancer staging because it allows to rapidly and non invasively evaluate the local extension of the tumor and to detect lymph adenopathies and distant metastases, with overall diagnostic accuracy values of 59-82% [6,12,14,[19][20][21]. In the preoperative staging of T parameter, CT reliability depends on the depth of tumor invasion.…”

Section: Ct Staging Of Esophageal Carcinomamentioning

confidence: 99%

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