Is paracervical block anesthesia for oocyte retrieval effective?

Corson, Stephen L.; Batzer, Frances R.; Gocial, Benjamin; Kelly, Maureen; Gutmann, Jacqueline N.; Go, Kathryn J.; English, Mary E.

doi:10.1016/s0015-0282(16)56828-9

Cited by 39 publications

(11 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A novel ®nding from the present trial was differentiation of pain between intervention groups at speci®c steps during oocyte retrieval. Outcome measures in previous trials did not differentiate between vaginal pain from administration of the paracervical block and insertion of the aspiration needle through the vaginal wall (Corson et al, 1994;Ng et al, 1999). On a note of caution, in the present trial, participants were asked to differentiate pain in a retrospective fashion.…”

Section: Discussionmentioning

confidence: 76%

“…Sample size estimation was based on evidence from a previous randomized trial of lidocaine paracervical block (Corson et al, 1994) in which the authors used a pain score scale from 0 to 4. A pain score difference of 0.5 on the scale from 0 to 4 was considered relevant.…”

Section: Protocolmentioning

confidence: 99%

“…Sedation is the technique most often used for pain relief during oocyte retrieval in the UK and the USA (Ditkoff et al, 1997;Bokhari and Pollard, 1999). Evidence from randomized, controlled trials suggests that pain relief is superior when adjunctive paracervical block is used in addition to sedation alone (Corson et al, 1994;Ng et al, 1999). Although paracervical block is the most commonly used form of regional anaesthesia for oocyte retrieval in the UK, most centres using sedation do so without adjunctive regional anaesthesia (Bokhari and Pollard, 1999).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Lidocaine vaginal gel versus lidocaine paracervical block for analgesia during oocyte retrieval

Tummon

Newton²,

Lee³

et al. 2004

Human Reproduction

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 76%

Section: Protocolmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Lidocaine vaginal gel versus lidocaine paracervical block for analgesia during oocyte retrieval

Tummon

Newton²,

Lee³

et al. 2004

Human Reproduction

View full text Add to dashboard Cite

show abstract

“…This means that the patient has some kind of light intravenous sedation. Studies have suggested superior pain relief with conscious sedation in combination with a PCB compared with sedation alone (Corson et al ., 1994; Ng et al ., 1999). However, owing to the fact that patients may experience pain during the procedure, many IVF groups still use general anaesthesia despite OPU then becoming more complicated and expensive since full anaesthesiological service for each procedure is required.…”

Section: Introductionmentioning

confidence: 99%

A randomized controlled study comparing pain experience between a newly designed needle with a thin tip and a standard needle for oocyte aspiration

Wikland

Blad

Bungum³

et al. 2011

Human Reproduction

View full text Add to dashboard Cite

BACKGROUNDUltrasound-guided transvaginal oocyte retrieval is often performed under local anaesthesia on an outpatient basis. The objective of this study was to compare the overall pain experience of a newly designed reduced needle (RN) compared with a thicker standard needle (SN).METHODSA prospective, randomized, multi-centre study was performed at four different clinics from June to December 2009. The oocyte aspiration was performed under local anaesthesia, either with a needle with a reduced diameter (0.9 mm) for the last 50 mm from the tip (RN) or with a SN (1.4 mm). A total of 257 patients were randomized (RN: n = 129; SN: n = 128). The primary endpoint was the overall pain experience self-assessed and registered by the patient on a visual analogue scale (VAS 0 mm = no pain to 100 mm = unbearable pain) immediately after the oocyte retrieval. Secondary end-points such as vaginal bleeding and several embryological parameters were also registered.RESULTSThe overall pain during the oocyte retrieval procedure was significantly lower in the RN group than in the SN group (mean 21.0 mm, SD 17.5 mm and median 19.0 mm versus mean 26.0 mm, SD 19.9 mm and median 24.0 mm; P = 0.040, difference between groups mean−5.0 mm, 95% CI: 9.7 to−0.4). This was also true when adjusting for baseline characteristics such as number of follicles, number of previous oocyte pick-up, body mass index and age, by a multiple linear regression analysis. Significantly more patients (40 of 126) had less than expected vaginal bleeding in the RN group when compared with the SN group (24 of 124; 32 versus 19%; P = 0.03 and 95% CI 1.7–23.0%). No differences were found between the two needles with regard to additional i.v. analgesia, aspiration time, oocyte recovery, fertilization, cleavage rate, number of good quality embryos, number of embryos for freezing and pregnancy rate.CONCLUSIONSOocyte aspiration performed with the newly designed thinner-tipped needle resulted in significantly less overall pain and less vaginal bleeding, without prolonging the retrieval procedure or influence the oocyte recovery rate, when compared with a SN.Clinicaltrials.gov: NCT00924885

show abstract

“…Russell et al described the use of PCB and conscious sedation administered by a certified registered nurse anesthetist (15). We used a simplified method for oocyte pick‐up including conscious sedation supplemented with PCB, which previously has been effective for oocyte retrieval after controlled ovarian hyperstimulation (5–7). All patients were discharged within two hours without experiencing discomfort during the following 30 hours.…”

Section: Discussionmentioning

confidence: 99%