Is Mycoplasma hominis a vaginal pathogen?

Arya, O P

doi:10.1136/sti.77.1.58

Cited by 38 publications

(42 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This data is also surprising because we expected that Candida should be prevalent in HIV-positive women resulting from a decline of natural immunity due to HIV. In previous studies [16,17] both M. hominis and Ureoplasma have been associated with BV [18], but in our study Ureoplasma was not found in HIVnegative women. This disparity with other studies may be due to the different detection protocols used.…”

Section: Discussioncontrasting

confidence: 50%

HIV-infected women of Burkina Faso: a “reservoir” of mycoplasma infection

Djigma¹,

Ouédraogo²,

Sagna³

et al. 2011

J Infect Dev Ctries

View full text Add to dashboard Cite

Introduction: The objective of this work was to assess the prevalence of bacterial vaginosis (BV) and genital mycoplasma colonization in 251 HIV-positive compared to 200 HIV-negative women at the Maternal and Child Health (MCH) service of Saint Camille Medical Center Ouagadougou (Burkina Faso). Methodology: After revealing the cervix with a speculum, we collected swabs of vaginal discharge for the detection of pathogenic bacteria. Results: Among HIV-positive and HIV-negative women, we identified respectively: Mycoplasma hominis (16.7% versus 5.5%); Ureaplasma urealyticum (16.3% versus 0.0%); co-infection M. hominis with U. urealyticum (13.14% versus 0.0%); Candida albicans (21.11% versus 41.5%); E. coli (9.96% versus 4.0%); and the presence of abundant vaginal discharge (27.5% versus 5.0%) respectively. The Nugent's score, utilized for the diagnosis of BV, was significantly higher in HIV-positive women (p < 0.001) associated with poor vaginal hygiene practices (p < 0.01) and no use of condoms (p < 0.01). Enterobacter, Klebsiella pneumonia, Klebsiella oxitocica, Staphylococcus epidermidis and Staphylococcus aureus, Streptococcus agalactiae, Trichomonas vaginalis, and Gardnerella vaginalis were also isolated, but in a low prevalence ranging from 0% to 5%. Conclusion: These results demonstrate that the HIV-positive women of Burkina Faso are frequently affected by BV and represent a reservoir for mycoplasma infection. Since these germs can lead to sterility and premature delivery, it is important to develop a policy of screening.

show abstract

Section: Discussioncontrasting

confidence: 50%

HIV-infected women of Burkina Faso: a “reservoir” of mycoplasma infection

Djigma¹,

Ouédraogo²,

Sagna³

et al. 2011

J Infect Dev Ctries

View full text Add to dashboard Cite

show abstract

“…Conversely, relapse of BV after treatment with metronidazole has been attributed to its lack of activity against M. hominis (66), but if the other organisms are eliminated, M. hominis may also disappear. Arya et al (18) found no role for M. hominis in the epidemiology of BV in a study of 341 women who harbored the organism in their vaginas, while Keane and colleagues (141) detected no difference in the occurrence of M. genitalium and Ureaplasma spp. in women with or without BV, but found M. hominis significantly more often in women with BV.…”

Section: Bacterial Vaginosismentioning

confidence: 99%

Mycoplasmas and Ureaplasmas as Neonatal Pathogens

Katz²,

2005

View full text Add to dashboard Cite

SUMMARY The genital mycoplasmas represent a complex and unique group of microorganisms that have been associated with a wide array of infectious diseases in adults and infants. The lack of conclusive knowledge regarding the pathogenic potential of Mycoplasma and Ureaplasma spp. in many conditions is due to a general unfamiliarity of physicians and microbiology laboratories with their fastidious growth requirements, leading to difficulty in their detection; their high prevalence in healthy persons; the poor design of research studies attempting to base association with disease on the mere presence of the organisms in the lower urogenital tract; the failure to consider multifactorial aspects of diseases; and considering these genital mycoplasmas only as a last resort. The situation is now changing because of a greater appreciation of the genital mycoplasmas as perinatal pathogens and improvements in laboratory detection, particularly with regard to the development of powerful molecular nucleic acid amplification tests. This review summarizes the epidemiology of genital mycoplasmas as causes of neonatal infections and premature birth; evidence linking ureaplasmas with bronchopulmonary dysplasia; recent changes in the taxonomy of the genus Ureaplasma; the neonatal host response to mycoplasma and ureaplasma infections; advances in laboratory detection, including molecular methods; and therapeutic considerations for treatment of systemic diseases.

show abstract

“…However, the bacterial pathogenesis of PID is unclear in cases where STI microbes are not detected, and where behavioural correlates of PID are not apparent. Many authors mention the role of facultative and anaerobic pathogens [4,5,7 -10], as well as Mycoplasma hominis and Ureaplasma urealyticum [11], as aetiological factors in PID.…”

Section: Introductionmentioning

confidence: 99%

Microbiology Profile in Women With Pelvic Inflammatory Disease in Relation to IUD Use

Viberga

Odlind

Lazdāne

et al. 2005

Infectious Diseases in Obstetrics and Gynecology

View full text Add to dashboard Cite

Objective. To study the microbial characteristics of patients with pelvic inflammatory disease (PID) and the possible impact of an intrauterine device (IUD) on the microbial environment in women presenting with PID. Methods. Case-control study, investigating 51 women with acute PID and 50 healthy women. Endocervical specimens for microbiological investigation were obtained at gynaecological examination. Results. IUD users with PID had significantly more Fusobacteria spp. and Peptostreptococcus spp. than non-IUD users with PID. The finding of combinations of several anaerobic or aerobic microbes was associated with a significantly increased risk of PID and with complicated PID. In IUD users, the combinations of several anaerobic/aerobic microbes were associated with an increased risk of PID, irrespective of duration of IUD use. Long-term IUD use appeared to be associated with an increased risk of a PID being complicated. Conclusion. The finding of several anaerobic or aerobic microbes appears to be associated with PID in users of IUD.

show abstract

Is Mycoplasma hominis a vaginal pathogen?

Cited by 38 publications

References 9 publications

HIV-infected women of Burkina Faso: a “reservoir” of mycoplasma infection

HIV-infected women of Burkina Faso: a “reservoir” of mycoplasma infection

Mycoplasmas and Ureaplasmas as Neonatal Pathogens

Microbiology Profile in Women With Pelvic Inflammatory Disease in Relation to IUD Use

Contact Info

Product

Resources

About