Is it possible for a simultaneous biomodification during acid etching on naturally caries-affected dentin bonding?

Hass, Viviane; Oliveira, Thais Bezerra da Maceno; Cardenas, Andrés Felipe Millán; Siqueira, Fabiana Suelen Figuerêdo de; Bauer, José; Abuna, Gabriel Flores; Sinhoreti, Mário Alexandre Coelho; Souza, Jullian Josnei de; Loguércio, Alessandro Dourado

doi:10.1007/s00784-020-03677-8

Cited by 9 publications

(7 citation statements)

References 47 publications

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“…Dentin etching with 35% PA tends to promote incomplete resin infiltration into the fully demineralized dentin and its collagen-rich organic matrix, resulting in the presence of denuded collagen fibrils at the bottom of the hybrid layer and degradation of the adhesive interface by MMPs. This led to the formulation of PAs containing MMP inhibitors (Vicente and Bravo 2008; Bernales Sender et al 2020) and bioactive components (Ibrahim et al 2019; Hass et al 2021) as they represent a valid alternative for enhancing bonding performance.…”

Section: Progress In Etching Strategiesmentioning

confidence: 99%

Progress in Dental Adhesive Materials

et al. 2023

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There have been significant advances in adhesive dentistry in recent decades, with efforts being made to improve the mechanical and bonding properties of resin-based dental adhesive materials. Various attempts have been made to achieve versatility, introducing functional monomers and silanes into the materials’ composition to enable the chemical reaction with tooth structure and restorative materials and a multimode use. The novel adhesive materials also tend to be simpler in terms of clinical use, requiring reduced number of steps, making them less technique sensitive. However, these materials must also be reliable and have a long-lasting bond with different substrates. In order to fulfill these arduous tasks, different chemical constituents and different techniques are continuously being developed and introduced into dental adhesive materials. This critical review aims to discuss the concepts behind novel monomers, bioactive molecules, and alternative techniques recently implemented in adhesive dentistry. Incorporating monomers that are more resistant to hydrolytic degradation and functional monomers that enhance the micromechanical retention and improve chemical interactions between adhesive resin materials and various substrates improved the performance of adhesive materials. The current trend is to blend bioactive molecules into adhesive materials to enhance the mechanical properties and prevent endogenous enzymatic degradation of the dental substrate, thus ensuring the longevity of resin–dentin bonds. Moreover, alternative etching materials and techniques have been developed to address the drawbacks of phosphoric acid dentin etching. Altogether, we are witnessing a dynamic era in adhesive dentistry, with advancements aiming to bring us closer to simple and reliable bonding. However, simplification and novelty should not be achieved at the expense of material properties.

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Section: Progress In Etching Strategiesmentioning

confidence: 99%

Progress in Dental Adhesive Materials

et al. 2023

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“…Micro-Raman spectroscopy revealed that the phosphate peaks in the 30D groups were more intense than those in the IM groups, and that the carbonate peaks remained constant. The phosphate spectral position classifies it as a crystal, while its peak width represents the degree of mineral crystallinity ( Hass et al, 2021 ). In other words, increased height and width of phosphate peak indicates remineralized samples.…”

Section: Discussionmentioning

confidence: 99%

Influence of silver fluoride plus potassium iodine on adhesive properties of primary carious dentin-resin interface: An in vitro study

da Luz,

Monteiro,

de França Lopes

et al. 2024

The Saudi Dental Journal

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“…Regarding collagen crosslinking, riboflavin (RF) was selected over other crosslinkers [ 44 ] as it has shown to significantly decrease the activity of matrix metalloproteinases, abundantly present in caries-affected dentin and responsible of the degradation of adhesive interfaces over time [ 45 , 46 ]. RF is a well-known water-soluble vitamin that is available in daily foods, due to its biocompatibility it has been extensively used for the treatment of ophthalmologic diseases [ 21 ], even an antibacterial effect of RF has been observed after its application in corneal collagen [ 47 ] and beneficial effects have been reported on dentin [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

ToF-SIMS Analysis of Demineralized Dentin Biomodified with Calcium Phosphate and Collagen Crosslinking: Effect on Marginal Adaptation of Class V Adhesive Restorations

et al. 2021

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This study aimed to assess the effect of biomodification before adhesive procedures on the tooth-restoration interface of class V restorations located in caries-simulated vs. sound dentin, and the quality of dentin surface by time-of-flight secondary ion mass spectrometry (ToF-SIMS). Class V cavities located on cervical dentin were prepared on the buccal surfaces of extracted human molars under the simulation of intratubular fluid flow. Two dentin types, i.e., sound and demineralized by formic-acid, were biomodified with 1% riboflavin and calcium phosphate (CaP) prior to the application of a universal adhesive (Clearfil Universal Bond) in etch and rinse or self-etch mode, and a conventional micro hybrid composite (Clearfil APX). Restorations were subjected to thermo mechanical fatigue test and percentages of continuous margins (% CM) before/after fatigue were compared. Bio modification of dentin surfaces at the molecular level was analyzed by Time-of-Flight Secondary Mass Spectometry (ToF-SIMS). % CM were still significantly higher in tooth-restoration interfaces on sound dentin. Meanwhile, biomodification with riboflavin and CaP had no detrimental effect on adhesion and in carious dentin, it improved the % CM both before and after loading. Etching carious dentin with phosphoric acid provided with the lowest results, leading even to restoration loss. The presence of molecule fragments of riboflavin and CaP were detected by ToF-SIMS, evidencing dentin biomodification. The adhesive interface involving carious dentin could be improved by the use of a collagen crosslinker and CaP prior to adhesive procedures.

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Is it possible for a simultaneous biomodification during acid etching on naturally caries-affected dentin bonding?

Cited by 9 publications

References 47 publications

Progress in Dental Adhesive Materials

Progress in Dental Adhesive Materials

Influence of silver fluoride plus potassium iodine on adhesive properties of primary carious dentin-resin interface: An in vitro study

ToF-SIMS Analysis of Demineralized Dentin Biomodified with Calcium Phosphate and Collagen Crosslinking: Effect on Marginal Adaptation of Class V Adhesive Restorations

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