Is Intraoperative Diffusion Tensor Imaging at 3.0T Comparable to Subcortical Corticospinal Tract Mapping?

Ostrý, Svatopluk; Belšán, T.; Otáhal, Jakub; Beneš, Vladimı́r; Netuka, David

doi:10.1227/neu.0000000000000087

Cited by 44 publications

(26 citation statements)

References 47 publications

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“…We summarize the existing literature in Table 1. These reports support a high linear correlation between distances to reconstructed tracts and positive DES intensities (Javadi et al, 2017, Maesawa et al, 2010, Ostry et al, 2013) or post-operative deficits (Prabhu et al, 2011). In addition to intra-operative morphological data, DTI sequences can be relatively quick to acquire and could be obtained intra-operatively in operating rooms with intra-operative MRI capability.…”

Section: Supratentorial Lesionssupporting

confidence: 63%

White matter tractography for neurosurgical planning: A topography-based review of the current state of the art

Essayed

Zhang

Unadkat

et al. 2017

NeuroImage: Clinical

181

166

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We perform a review of the literature in the field of white matter tractography for neurosurgical planning, focusing on those works where tractography was correlated with clinical information such as patient outcome, clinical functional testing, or electro-cortical stimulation. We organize the review by anatomical location in the brain and by surgical procedure, including both supratentorial and infratentorial pathologies, and excluding spinal cord applications. Where possible, we discuss implications of tractography for clinical care, as well as clinically relevant technical considerations regarding the tractography methods.We find that tractography is a valuable tool in variable situations in modern neurosurgery. Our survey of recent reports demonstrates multiple potentially successful applications of white matter tractography in neurosurgery, with progress towards overcoming clinical challenges of standardization and interpretation.

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Section: Supratentorial Lesionssupporting

confidence: 63%

White matter tractography for neurosurgical planning: A topography-based review of the current state of the art

Essayed

Zhang

Unadkat

et al. 2017

NeuroImage: Clinical

181

166

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“…Consequently, this study was not designed to measure the accuracy of the tractography results intraoperatively. To answer this additional research question and to further validate DTI tractography results, future studies are required which either use intraoperative MRT/DTI (Nimsky et al, 2005a, Nimsky et al, 2005b, Nimsky et al, 2006, Nimsky, 2011, Ostrý et al, 2013, Shahar et al, 2014) or avoid the brain shift by means of stereotactic approaches (Forster et al, 2015). …”

Section: Discussionmentioning

confidence: 99%

Functional MRI vs. navigated TMS to optimize M1 seed volume delineation for DTI tractography. A prospective study in patients with brain tumours adjacent to the corticospinal tract

Lucas

Tursunova

Neuschmelting

et al. 2017

NeuroImage: Clinical

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BackgroundDTI-based tractography is an increasingly important tool for planning brain surgery in patients suffering from brain tumours. However, there is an ongoing debate which tracking approaches yield the most valid results. Especially the use of functional localizer data such as navigated transcranial magnetic stimulation (nTMS) or functional magnetic resonance imaging (fMRI) seem to improve fibre tracking data in conditions where anatomical landmarks are less informative due to tumour-induced distortions of the gyral anatomy. We here compared which of the two localizer techniques yields more plausible results with respect to mapping different functional portions of the corticospinal tract (CST) in brain tumour patients.MethodsThe CSTs of 18 patients with intracranial tumours in the vicinity of the primary motor area (M1) were investigated by means of deterministic DTI. The core zone of the tumour-adjacent hand, foot and/or tongue M1 representation served as cortical regions of interest (ROIs). M1 core zones were defined by both the nTMS hot-spots and the fMRI local activation maxima. In addition, for all patients, a subcortical ROI at the level of the inferior anterior pons was implemented into the tracking algorithm in order to improve the anatomical specificity of CST reconstructions. As intra-individual control, we additionally tracked the CST of the hand motor region of the unaffected, i.e., non-lesional hemisphere, again comparing fMRI and nTMS M1 seeds. The plausibility of the fMRI-ROI- vs. nTMS-ROI-based fibre trajectories was assessed by a-priori defined anatomical criteria. Moreover, the anatomical relationship of different fibre courses was compared regarding their distribution in the anterior-posterior direction as well as their location within the posterior limb of the internal capsule (PLIC).ResultsOverall, higher plausibility rates were observed for the use of nTMS- as compared to fMRI-defined cortical ROIs (p < 0.05) in tumour vicinity. On the non-lesional hemisphere, however, equally good plausibility rates (100%) were observed for both localizer techniques. fMRI-originated fibres generally followed a more posterior course relative to the nTMS-based tracts (p < 0.01) in both the lesional and non-lesional hemisphere.ConclusionNTMS achieved better tracking results than fMRI in conditions when the cortical tract origin (M1) was located in close vicinity to a brain tumour, probably influencing neurovascular coupling. Hence, especially in situations with altered BOLD signal physiology, nTMS seems to be the method of choice in order to identify seed regions for CST mapping in patients.

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“…As reported by Ostry et al, 34 5 studies performed a quantitative analysis of the relationship between the distance from CST and the stimulation intensity but provided variable results. [33][34][35][36][37] Among these studies, 4 found a linear correlation between the distance and the stimulation intensity, 33-36 whereas a nonlinear relationship was found in 1 study.…”

Section: Discussionmentioning

confidence: 99%

Navigated Transcranial Magnetic Stimulation for “Somatotopic” Tractography of the Corticospinal Tract

Conti¹,

Raffa²,

Granata

et al. 2014

Operative Neurosurgery

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Is Intraoperative Diffusion Tensor Imaging at 3.0T Comparable to Subcortical Corticospinal Tract Mapping?

Cited by 44 publications

References 47 publications

White matter tractography for neurosurgical planning: A topography-based review of the current state of the art

White matter tractography for neurosurgical planning: A topography-based review of the current state of the art

Functional MRI vs. navigated TMS to optimize M1 seed volume delineation for DTI tractography. A prospective study in patients with brain tumours adjacent to the corticospinal tract

Navigated Transcranial Magnetic Stimulation for “Somatotopic” Tractography of the Corticospinal Tract

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