2009
DOI: 10.1007/s00464-009-0746-2
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Is endoscopic closure with clips effective for both diagnostic and therapeutic colonoscopy-associated bowel perforation?

Abstract: Conservative management by immediate endoscopic closure with clips can be effective for the treatment of colonic perforations detected during colonoscopy. Conservative management also may be tried cautiously for stable patients who have radiologically proven colonoscopy-associated perforations without endoscopic evidence.

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Cited by 59 publications
(33 citation statements)
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“…Endoscopic closure is effective in creating a leak-proof seal of the perforation, healing of the perforation, preventing peritonitis, limiting peritoneal adhesions, and avoiding surgery. 47,[58][59][60][61][62][63][64][65][66][67][68][69][70] …”
Section: Managementmentioning
confidence: 99%
“…Endoscopic closure is effective in creating a leak-proof seal of the perforation, healing of the perforation, preventing peritonitis, limiting peritoneal adhesions, and avoiding surgery. 47,[58][59][60][61][62][63][64][65][66][67][68][69][70] …”
Section: Managementmentioning
confidence: 99%
“…31,33 Contrastly therapeutic polypectomy induced perforation has a smaller defect (mean size 5.8 mm), and most patients can be treated conservatively. 31,33 In addition, EMR related perforation can be immediately recognized if there is a "target sign" (Fig. 1) indicating muscularis propria injury in the resected specimen.…”
Section: 24mentioning
confidence: 99%
“…4) provided successful closure rate at 75.86% to 95.65% in retrospective series. 33,[92][93][94][95] Predictors for the need of surgery within 24 hours after clipping are perforation size 10 mm or more, leukocytosis, fever, severe abdominal pain, and large amount of peritoneal free air indicated by a distance between right diaphragm and upper border of liver of 3 cm or more.…”
Section: Duodenal Perforationmentioning
confidence: 99%
“…In delayed recognition, clipping should be considered only if the patient is stable and a specific site is highly suspected, mainly in rectosigmoid location [112]. When comparing diagnostic and therapeutic colonoscopy-associated perforation, the former is usually larger, irregular and sometimes not immediately recognized in terms of location, thus it is more prompt for surgical approach [113]. Surgery is indicated in patients with large perforations, generalized peritonitis or ongoing sepsis as well as in patients with concomitant pathology, such as a large sessile polyp likely to be a carcinoma, unremitting colitis, or obstructing colonic lesion.…”
Section: Location Particularitiesmentioning
confidence: 99%